A preparation method of magnetic gel for assisting endoscopic submucosal dissection

Abstract

The invention discloses magnetic gel for assisting endoscopic mucosal dissection. The magnetic gel is prepared mainly from permanent magnetic material microparticles, a sodium alginate solution and acalcium chloride solution, and medical dye can also be added; a preparation method thereof comprises the following steps: preparing the sodium alginate solution, adding the permanent magnetic materialmicroparticles, uniformly mixing to obtain a solution A, and using the calcium chloride solution or a mixed solution of the calcium chloride solution and the medical dye as a solution B; filling a double-cavity synchronous injection device with the solution A and the solution B respectively, and injecting an appropriate amount of an uniformly mixed solution into a mucosal lesion to be dissected according to the size of the lesion during using, wherein the uniformly mixed solution can form the magnetic gel in the lesion within a short time. The application system comprises the double-cavity synchronous injection device for injecting the uniformly mixed solution into the mucosal lesion to be dissected, and a detachable magnetic ring at the head end of an endoscope, wherein the uniformly mixed solution forms the magnetic gel after injection. Through magnetic attraction between the magnetic gel and the detachable magnetic ring at the head end of the endoscope, a pulling force opposite toa muscular layer is provided, so that the dissection between mucosa and muscular layer is facilitated; the invention has the advantages of convenience in operation, reduction in surgical difficulty and the like.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a magnetic gel for assisting endoscopic mucosal dissection, its preparation and its application system. Background technique [0002] Endoscopic mucosal dissection is one of the important methods for the treatment of gastrointestinal mucosal lesions (including early gastrointestinal cancer, submucosal tumors, giant flat polyps of the gastrointestinal tract, etc.). The key operation in the implementation of endoscopic mucosal dissection is to use submucosal injection to separate the mucosal layer from the muscular layer and lift up the lesion, and then gradually peel off the lesion with an electric knife. The disadvantage is that the mucosa of the lesion lacks the traction force in the opposite direction to the muscular layer, so that the gap between the mucosa and the muscular layer is not clearly exposed, which is not conducive to the stripping of the elect...

AI Technical Summary

Problems solved by technology

The disadvantage is that the mucosa of the lesion lacks the traction force in the opposite direction to the muscular layer, so that the gap between the mucous membrane and the muscular layer is not clearly exposed, which is not conducive to the stripping of the electric knife between the mucous membrane and the muscular layer.

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