A traditional Chinese medicine compound external preparation for treating hormone-dependent dermatitis and its preparation method and application

Abstract

The invention provides a traditional Chinese herbal compound external preparation for treating hormone dependent dermatitis. An effective part is prepared by the following Chinese herbal medicines according to the parts by weight: 5-80 parts of rhizoma polygonati, 5-60 parts of flos lonicerae, 5-60 parts of flos chrysanthemi, 5-60 parts of poria cocos and 3-60 parts of liquorice. The invention further discloses a preparation method and an application of the preparation. The preparation is capable of mainly using the rhizoma polygonati as a monarch drug, using the flos lonicerae and the flos chrysanthemi as ministerial drugs together, using the poria cocos as an adjuvant, and using the liquorice as a conductant drug for reconciling the drug properties of a whole prescription, using the effects of nourishing Yin and moistening dryness, removing pathogenic heat from blood and toxic material from body, clearing away heat and removing dampness, and dispelling wind and arresting itching as abasic treatment rule of the preparation, and promoting the repair of the hormone dependent dermatitis. The prescription is simple, accords with a traditional Chinese medicine theory of treating the hormone dependent dermatitis, and has the support and evidence of modern pharmacology achievements of each single Chinese herb. An extracting process for the compound effective part is simple, the effective ingredient content is high, the introduction of non-effective ingredients is reduced, a preparation technology is scientific, a transmittance rate of the effective ingredients in a pathologicaltissue is high, the animal experiment and human body trial effect is remarkable without the adverse reaction, the use is convenient and the adaptability is good.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for external use, its preparation method and application, in particular to a traditional Chinese medicine compound preparation for treating hormone-dependent dermatitis, its preparation method and its application. Background technique [0002] Steroid-dependent dermatitis is corticosteroid-dependent dermatitis, also known as glucocorticoid addiction dermatitis or topical glucocorticoid withdrawal dermatitis, is an inflammatory skin disease caused by inappropriate topical topical glucocorticoids, and the clinical manifestations are localized Gradually atrophy and thinning of the epidermis, telangiectasia, telangiectasia, thin skin, flushing, edema, erythema, desquamation, papules, acne-like and rosacea-like rashes, etc., with local tingling and burning Pain, itching, dryness, tightness, etc., and the skin lesions were relieved or disappeared when the steroids were used again, a...

AI Technical Summary

Problems solved by technology

[0017] To sum up, the current traditional Chinese medicine compound prescriptions for the clinical treatment of hormone-dependent dermatitis, whether taken orally or externally, are mostly cold and cool medicines that nourish yin and cool serum, heat and detoxify, but long-term use can easily affect the gastrointestinal tract and other organs. function of organs, and even lead to irreversible drug-induced organ damage; the existing preparation technologies and processes of traditional Chinese medicine compound external preparations, such as water, tincture, paste, etc. agent or ointment, the content of effective ingredients in the preparation is low, the skin is irritating, the penetration rate of active ingredients is low, and it is difficult to achieve an effective therapeutic concentration

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