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Eye drop for repairing injured cytokines of eyes and preparation method

A technology of cytokines and eye drops, applied in the field of biological stem cells, can solve the problems of latent virus and pathogenic microorganism infection and low probability of transmission, and achieve the effect of promoting structural reconstruction and regeneration repair, ensuring uniformity, and promoting wound healing

Inactive Publication Date: 2018-11-23
天津欣普赛尔生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

⑤Infection and transmission of latent viruses and pathogenic microorganisms are relatively low

Method used

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  • Eye drop for repairing injured cytokines of eyes and preparation method
  • Eye drop for repairing injured cytokines of eyes and preparation method
  • Eye drop for repairing injured cytokines of eyes and preparation method

Examples

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Comparison scheme
Effect test

Embodiment 1

[0029] As shown in the figure, the present invention provides an eye drop for repairing eye damage cytokines, which comprises 10-15g of retinoic acid, 25-30g of taurine, and 12-18g of transparent Hyaluronic acid, 2-5 mg benzalkonium bromide, and the rest of the umbilical cord mesenchymal stem cell supernatant.

Embodiment 2

[0031] As shown in the figure, the present invention provides an eye drop for repairing eye damage cytokines, which comprises 13g of retinoic acid, 27g of taurine, 15g of hyaluronic acid, and 3mg of benzalkonium per liter of eye drop. ammonium bromide and the rest of the umbilical cord mesenchymal stem cell supernatant.

[0032] The preparation method of eye drops for repairing mammalian eye damage cytokines is characterized in that it comprises the following steps:

[0033] (1) Select the umbilical cord tissue and conduct the test: the umbilical cord donor is the pregnant woman ≤33 years old, and the pregnancy period is ≤40 weeks. Within 10 seconds after the newborn is delivered, use two hemostatic forceps at a place 5-8cm away from the umbilical cord of the newborn. Live, ligate two places from between the two forceps, cut the umbilical cord from the middle, select 15-18cm, put it in a collection bottle containing collection liquid, and collect 3-5ml of maternal peripheral b...

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Abstract

The invention provides an eye drop for repairing injured cytokines of eyes and a preparation method, and relates to the technical field of biological stem cells. Every 1 liter of eye drop comprises the following components according to a weight ratio: 10 to 15g of retinoic acid, 25 to 30g of taurine, 12 to 18g of hyaluronic acid, 2 to 5mg of benzalkonium bromide and the balance of umbilical cord mesenchymal stem cell supernatant. The eye drop has the advantages that the microenvironment of the eyes is improved; the stem cells are accelerated to migrate and differentiate to the injured part ofthe eyes, and are used as seed cells to participate in the repair and regeneration of the injured tissues of the eyes, so as to reach the purposes of repairing the tissue cells of the eyes and recovering the vision function of the eyes.

Description

technical field [0001] The invention relates to the technical field of biological stem cells, in particular to an eye drop for repairing eye damage cytokines and a preparation method. Background technique [0002] As the most important organ in the body of mammals, the eye is responsible for distinguishing all things. Once the eye is damaged, all aspects of life will be greatly affected. At present, the repair and treatment of the eye is also a worldwide problem. [0003] Mesenchymal stem cells are a research branch of stem cells. Stem cells are a type of cells with self-replication and multi-directional differentiation capabilities. They can continuously self-renew and have unique factor secretion functions. Under certain conditions, they can transform into a or a variety of cells that make up human tissues or organs. Stem cells are the origin cells of the body and the progenitor cells that form various tissues and organs of the human body. Mesenchymal stem cells not only...

Claims

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Application Information

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IPC IPC(8): A61K35/28A61K9/08A61K47/18A61P27/02A61K31/185A61K31/203A61K31/728
CPCA61K9/0048A61K9/08A61K31/185A61K31/203A61K31/728A61K35/28A61K47/18A61P27/02A61K2300/00
Inventor 赵阳鲁振宇洪敬欣张冰晶
Owner 天津欣普赛尔生物医药科技有限公司
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