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Pharmaceutical composition, medicine and application thereof

A composition and drug technology, applied in the field of medicine, can solve the problems of general effect, influence curative effect, influence chemotherapy on schedule, according to the amount, etc., and achieve the effect of reducing numbness of hands and feet and achieving significant therapeutic effect.

Inactive Publication Date: 2019-01-18
PEKING UNIV SHENZHEN HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although HFS does not endanger the life of the patient, it affects the daily life and actions of the patient, affects the quality of life of the patient, and often affects the schedule and dose of chemotherapy, affecting the curative effect
[0005] In order to alleviate the hand-foot syndrome of tumor patients, the use of vitamin B6 and other drugs for treatment has been disclosed in the related art, but according to the results of clinical experiments, vitamin B6 and other drugs have certain therapeutic effects on hand-foot syndrome, but the effect is general and not effective. significant therapeutic effect

Method used

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  • Pharmaceutical composition, medicine and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Get 10 parts by weight of Notoginseng powder and 5 parts by weight of Caulis Spatholobus powder, fully stir and mix the above-mentioned parts by weight of Notoginseng powder and Caulis Spatholobus powder, and then use 70%-75% (concentration) alcohol to prepare Paste or paste.

Embodiment 2

[0034] Get 8 parts by weight of notoginseng powder and 6 parts by weight of millet root powder, fully stir and mix the above-mentioned parts by weight of notoginseng powder and millet root powder, and then use 70%-75% (concentration) alcohol to prepare Paste or paste.

Embodiment 3

[0036] Get 5 parts by weight of notoginseng powder and 8 parts by weight of Caulis Spatholobus powder, fully stir and mix the above-mentioned parts by weight of notoginseng powder and Caulis Spatholobus powder, and then use 70%-75% (concentration) alcohol to prepare Paste or paste.

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PUM

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Abstract

The invention discloses a pharmaceutical composition, a medicine and an application thereof, which are used for external application treatment of hand-foot syndrome in tumor patients, wherein, the pharmaceutical composition comprises notoginseng radix, caulis Spatholobi, and optionally sanguis Draxonis. The pharmaceutical composition of the invention has remarkable therapeutic effect in treating hand-foot syndrome of tumor patients, and can obviously alleviate symptoms such as numbness of hands and feet, swelling, erythema, wet desquamation, ulcer and the like of tumor patients.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating hand-foot syndrome of tumor patients. Background technique [0002] Hand-foot syndrome (HFS): also known as palmoplantar sensory loss erythema (PPES), the main clinical manifestations are heat, pain, and erythematous swelling of the fingers / toes. In severe cases, it develops into desquamation, ulcers, and severe pain, which affects daily life. Life. [0003] It was reported in 1984 by Jacob Lokich and Chery Moore of Dekenis Hospital, England, Harvard Medical School, when it was observed that this specificity occurred in 25% of patients receiving repeated long-term chemotherapy with 5-Fu or liposomal doxorubicin. Sexual skin syndrome. [0004] Drugs likely to cause hand-foot syndrome: chemotherapy drugs: capecitabine, liposomal doxorubicin, cytarabine, docetaxel, vinorelbine, and continuous infusion of doxorubicin, gemcitabi...

Claims

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Application Information

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IPC IPC(8): A61K36/486A61K36/896A61P17/00A61P29/00A61P17/02
CPCA61K36/258A61K36/486A61K36/896A61P17/00A61P17/02A61P29/00A61K2300/00
Inventor 王丽
Owner PEKING UNIV SHENZHEN HOSPITAL
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