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A kind of traditional Chinese medicine composition for treating psoriasis

A composition and technology for psoriasis, applied in the directions of drug combinations, pharmaceutical formulations, skin diseases, etc., can solve the problems of large side effects, low cure rate, long treatment period, etc., and achieve small side effects, low recurrence rate, and fast onset of effect. Effect

Active Publication Date: 2021-07-27
THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional Chinese medicine composition solves the problems of long treatment period, low cure rate, large side effects and high recurrence rate in the existing psoriasis treatment. Advantages of relapse

Method used

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  • A kind of traditional Chinese medicine composition for treating psoriasis
  • A kind of traditional Chinese medicine composition for treating psoriasis
  • A kind of traditional Chinese medicine composition for treating psoriasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] A traditional Chinese medicine composition for treating psoriasis, a medicament made of the following raw materials in proportions by weight:

[0066] Coptidis 12g, Curcuma 12g, Banzhilian 30g, Hedyotis 30g, Codonopsis 12g, Astragalus 21g, Coix seed 30g, Ophiopogon japonicus 15g, Baishao 21g, Atractylodes macrocephala 21g, licorice 6g.

[0067] A preparation method for oral capsules for treating psoriasis, the steps are as follows:

[0068] After rinsing the above raw materials, add 420g of water and decoct for 15 minutes, separate the solid and liquid, then add 420g of water and decoct for 15 minutes, combine the two decoctions, filter through a 120-mesh sieve, concentrate, dry, pulverize, and sterilize, then add capsules, ready to serve.

Embodiment 2

[0070] A traditional Chinese medicine composition for treating psoriasis, a medicament made of the following raw materials in proportions by weight:

[0071] Coptidis 10g, Curcuma 10g, Banzhilian 35g, Hedyotis 26g, Codonopsis 15g, Astragalus 20g, Coix seed 24g, Ophiopogon japonicus 18g, Baishao 25g, Atractylodes macrocephala 22g, licorice 5g.

[0072] Preparation method: with embodiment 1.

Embodiment 3

[0074] A traditional Chinese medicine composition for treating psoriasis, a medicament made of the following raw materials in proportions by weight:

[0075] Coptidis 15g, Curcuma 15g, Banzhilian 26g, Hedyotis 35g, Codonopsis 10g, Astragalus 25g, Coix seed 32g, Ophiopogon japonicus 11g, Baishao 17g, Atractylodes macrocephala 17g, licorice 7g.

[0076] Preparation method: with embodiment 1.

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Abstract

The present invention relates to a traditional Chinese medicine composition for treating psoriasis. . The traditional Chinese medicine composition of the present invention has been confirmed by the results of cytological experiments, can effectively inhibit the proliferation of human immortalized keratinocyte HaCaT cells, and induce its apoptosis; and the traditional Chinese medicine composition can also significantly reduce the CXCL1 and CCL20 in HaCaT cells , CXCL8, IL-6, IL-18 expression, the results of clinical experiments show that it has the advantages of quick onset, good curative effect, small side effects and low recurrence rate.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating psoriasis, which belongs to the technical field of traditional Chinese medicine. Background technique [0002] Psoriasis is a common clinical skin disease that can affect the skin, nails, mucous membranes and joints of patients. The course of psoriasis is long, lingering and difficult to heal, and it is easy to relapse. Most of them accompany lifelong psoriasis. mental and economic burden. The specific etiology and pathogenesis of psoriasis are complex and have not yet been fully elucidated. The pathogenesis of psoriasis involves many links such as immune system disorder, angiogenesis and keratinocyte proliferation. Various factors interact to form a network, which also leads to the multicenter of psoriasis pathogenesis and the complexity of psoriasis prevention and treatment. [0003] The current treatment of psoriasis mainly includes inhibiting the excessive prolifer...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P17/06
Inventor 孙淑娜
Owner THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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