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A method based on the principle of ffr to quickly determine the size model of vascular stenosis resistance and microcirculation resistance

A vascular stenosis and resistance technology, applied in catheters, cardiac catheters, etc., can solve the problems of long time and complicated calculation process.

Active Publication Date: 2022-04-22
BEIJING UNIV OF TECH
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  • Claims
  • Application Information

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Problems solved by technology

However, this method takes a long time from obtaining the patient's CT data to finally calculating the FFR. The general calculation cycle takes 24 hours, and the calculation process is very cumbersome.

Method used

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  • A method based on the principle of ffr to quickly determine the size model of vascular stenosis resistance and microcirculation resistance
  • A method based on the principle of ffr to quickly determine the size model of vascular stenosis resistance and microcirculation resistance
  • A method based on the principle of ffr to quickly determine the size model of vascular stenosis resistance and microcirculation resistance

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Experimental program
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Embodiment 1

[0031] Obtain the ct image of the patient, and systolic blood pressure: 117mmHg; diastolic blood pressure: 61mmHg; cardiac output: 4.29L / min. The three-dimensional coronary artery model of the patient was reconstructed by using mimics software, and the location of the stenosis was marked. Then use geomagic software to measure and record the diameter of each segment of blood vessels on the three-dimensional model, and measure the minimum diameter of the lesion at the same time, and calculate the stenosis rate. Because the patient's cardiac output is 4.29L / min, the total coronary flow is 2.86ml / s; the right coronary flow is 1.144ml / s; the left coronary flow is 1.716ml / s.

[0032] The lesion was located at grade 21 in the left crown. D. 11 =3.84mm; D 12 = 1.85mm; D 21 =3.32mm; D 22 =1.15mm; calculated Q 21 = 1.48ml / s. The minimal stenosis diameter of this diseased vessel is .99mm, so its stenosis rate is 70%.

[0033] Substitute systolic, diastolic, blood flow and stenosi...

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Abstract

The invention relates to a method for establishing a model for rapidly judging blood vessel stenosis resistance and microcirculation resistance based on the FFR principle, belonging to the field of model establishment. It is a method based on the principle of FFR to quickly judge whether coronary stenosis causes myocardial ischemia. Obtain the systolic blood pressure, diastolic blood pressure, cardiac output, and CT images of the patient; then based on the CT images of the patient, reconstruct the three-dimensional model of the coronary artery, measure and record the diameter of each branch vessel; and then distribute the blood flow. Based on the data collected from multiple groups of systolic blood pressure, diastolic blood pressure, blood flow and stenosis rate, a logistic regression equation was established. Then, the above parameters were substituted into the established logistic regression model to judge the vascular stenosis resistance and microcirculation resistance, and then preliminarily judge whether coronary stenosis caused myocardial ischemia. This method is computationally fast.

Description

technical field [0001] The invention provides a model based on the FFR principle, which can quickly determine the resistance of blood vessel stenosis and microcirculation resistance, and further determine whether myocardial ischemia is caused, and belongs to the field of model establishment. Background technique [0002] Anatomically, there is no absolute correlation between the degree of coronary artery stenosis and myocardial functional ischemia, that is, myocardial ischemia does not necessarily have a simple positive correlation with coronary artery stenosis. Therefore, it is of great significance to clarify the quantitative relationship between coronary stenosis and myocardial ischemia clinically in order to guide the selection, evaluation and prognosis of treatment strategies for stenotic lesions. In the past, the diagnosis of coronary heart disease was generally performed by means of non-invasive examination (CTA), which can effectively show the lesion degree and locat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/02
CPCA61B5/02007
Inventor 刘有军冯月毛伯䶮靳纯博
Owner BEIJING UNIV OF TECH
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