Surfactant-containing spray of anticholinergic drug

A technology for anticholinergic drugs and surfactants, which is applied in the field of sprays of anticholinergic drugs containing surfactants, and can solve the problems of propellant toxicity, unsuitability for heart disease patients, and easy explosion.
CN110876807AInactive Publication Date: 2020-03-13TIANJIN JINYAO GRP
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TIANJIN JINYAO GRP
Publication Date
2020-03-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a medicine tiotropium bromide spray for treating respiratory diseases, especially asthma, chronic obstructive pneumonia, trachitis and the like. An inhalable surfactant enables the spray particle size, spray time and spray speed of the composition to be more suitable by adjusting the surface tension of a spray pharmaceutical composition of M1, M2 and / or M3 receptor anticholinergic drugs without propellants.
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Description

Technical field:

[0001] The present invention relates to the drug tiotropium bromide spray for treating respiratory diseases, especially asthma, chronic obstructive pneumonia, bronchitis, etc., wherein the inhalable surfactant can regulate M1, M2 and / or M3 receptors not containing propellant The surface tension of the spray pharmaceutical composition of the anticholinergic drug makes the spray particle size, spray time and spray speed of the composition more suitable. Background technique:

[0002] Asthma is a chronic airway inflammation characterized by reversible airway obstruction and increased airway responsiveness. Airway obstruction is caused by two factors: increased secretions caused by bronchial mucosal inflammation, mucosal edema, and smooth muscle spasm stimulated by inflammation; while asthma Increased airway reactivity is also a result of damage to the bronchial epithelium due to airway inflammation. It is recognized that only by controlling the inflammation of...

Claims

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