Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease and its application

A technique for vascular disease and composition, which is applied in the field of traditional Chinese medicine and achieves the effects of simple preparation method, low cost and improving the degree of vascular disease of lower extremities

Active Publication Date: 2021-11-16
SHANGHAI PUTUO DISTRICT LIQUN HOSPITAL
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the lower the ankle-brachial index, the worse the prognosis, and the prognosis of patients with multi-vessel involvement in the lower extremities is worse than that of those with single-vessel involvement

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease and its application
  • A traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease and its application
  • A traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1 - Preparation of the composition of the present invention

[0013] In the present invention (30 parts of Poria cocos, 30 parts of plantain seeds, 30 parts of honeysuckle, 15 parts of Achyranthes, and 10 parts of Radix Radix et Rhizoma), the traditional Chinese medicine decoction pieces in the prescription are crushed into powder, and the raw material powder is obtained according to the weight ratio of the above pharmaceutical composition ingredients, Mix well, add water to soak for 1 hour, cook twice in a steam jacketed pot, combine the secondary filtrate, let it settle for 10-12 hours, take the supernatant and decoct and condense it into a decoction according to the amount of each dose of the raw material. , divided into bottles, steam sterilized.

Embodiment 2

[0014] Example 2 The second preparation of the composition of the present invention

[0015] In the present invention (35 parts of Poria, 30 parts of psyllium, 30 parts of honeysuckle, 15 parts of Achyranthes, and 10 parts of Radix Radix et Rhizoma), the traditional Chinese medicine decoction pieces in the recipe are rolled into powder, and the raw material powder is obtained according to the weight ratio of the above pharmaceutical ingredients, Mix well, add water to soak for 1 hour, cook twice in a steam jacketed pot, combine the secondary filtrate, let it settle for 10-12 hours, take the supernatant and decoct and condense it into a decoction according to the amount of each dose of the raw material. , divided into bottles, steam sterilized.

Embodiment 3

[0016] Example 3 Three preparations of the composition of the present invention

[0017] In the present invention (32 parts of Poria cocos, 30 parts of plantain seeds, 30 parts of honeysuckle, 15 parts of Achyranthes, and 10 parts of Radix Radix et Rhizoma), the traditional Chinese medicine decoction pieces in the prescription are crushed into powder, and the raw material powder is obtained according to the weight ratio of the above pharmaceutical composition ingredients, Mix well, add water to soak for 1 hour, cook twice in a steam jacketed pot, combine the secondary filtrate, let it settle for 10-12 hours, take the supernatant and decoct and condense it into a decoction according to the amount of each dose of the raw material. , divided into bottles, steam sterilized.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease. The traditional Chinese medicine composition is made of the following raw materials in parts by weight: 30-50 parts of poria cocos, 30 parts of plantago seed, 30-90 parts of honeysuckle flower, 15 parts of Achyranthes bidentata, 10‑30 parts of Viola dichotoma. The invention also provides the application of the traditional Chinese medicine composition. The invention proves through pharmacology and drug efficacy experiments that it can improve the degree of vascular disease in the lower limbs of diabetic rats, improve the blood coagulation function of diabetic rats, and improve the inflammation status of diabetic rats. Therefore, it can be used to prepare medicines for preventing and treating diseases related to diabetic lower extremity vascular lesions. The preparation method of the extract or the composition of the invention is simple and the cost is low, and the invention provides a new drug source for preventing and treating diseases related to diabetic lower extremity vascular lesions.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease and its application. Background technique [0002] Diabetic lower extremity vascular disease is a common complication of diabetes. Lower extremity vascular disease mainly refers to lower extremity arterial disease, which is a component of peripheral arterial disease and manifests as stenosis or occlusion of lower extremity arteries. The risk of developing lower extremity arterial disease in diabetic patients is significantly higher than that in non-diabetic patients, and lower extremity vascular disease has an earlier age of onset, more severe disease, more extensive lesions, and worse prognosis. Lower extremity arterial disease shares common pathological mechanisms with coronary artery disease, cardiovascular and cerebrovascular disease and other...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/86A61P3/10A61P9/14
CPCA61K36/076A61K36/21A61K36/355A61K36/68A61K36/86A61P3/10A61P9/14A61K2300/00
Inventor 王燕张云凤陆艳严怡婷侯波任子彦王子澄
Owner SHANGHAI PUTUO DISTRICT LIQUN HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com