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Traditional Chinese medicine composition for treating and preventing diabetes lower limb vasculopathy and application thereof

A technique for vascular disease and composition, which is applied in the field of traditional Chinese medicine and achieves the effects of improving the degree of vascular disease of lower extremities, a simple preparation method and improving blood coagulation function.

Active Publication Date: 2020-07-28
SHANGHAI PUTUO DISTRICT LIQUN HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the lower the ankle-brachial index, the worse the prognosis, and the prognosis of patients with multi-vessel involvement in the lower extremities is worse than that of those with single-vessel involvement

Method used

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  • Traditional Chinese medicine composition for treating and preventing diabetes lower limb vasculopathy and application thereof
  • Traditional Chinese medicine composition for treating and preventing diabetes lower limb vasculopathy and application thereof
  • Traditional Chinese medicine composition for treating and preventing diabetes lower limb vasculopathy and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1 Composition-preparation of the present invention

[0013] The present invention (30 parts of Poria cocos, 30 parts of Semen Plantaginis, 30 parts of Honeysuckle, 15 parts of Achyranthes bidentata, 10 parts of Viola Dipin) grinds the decoction pieces of the traditional Chinese medicine in the prescription into a powder, and takes the raw material powder according to the weight ratio of the above drug prescription components, Mix well, add water to soak for 1 hour, cook twice in a steam jacketed pot, combine the second filtrate, let it stand for 10-12 hours, take the supernatant and decoct and concentrate it into a decoction according to the amount of each dose of raw medicine , divided into bottles, and steam sterilized.

Embodiment 2

[0014] Embodiment 2 The composition of the present invention two preparations

[0015] The present invention (35 parts of Poria cocos, 30 parts of Semen Plantaginis, 30 parts of Honeysuckle, 15 parts of Achyranthes bidentata, 10 parts of Zihua Diding) grinds the decoction pieces of the traditional Chinese medicine in the prescription into powder, and takes the raw material powder according to the weight ratio of the above drug prescription components, Mix well, add water to soak for 1 hour, cook twice in a steam jacketed pot, combine the second filtrate, let it stand for 10-12 hours, take the supernatant and decoct and concentrate it into a decoction according to the amount of each dose of raw medicine , divided into bottles, and steam sterilized.

Embodiment 3

[0016] Embodiment 3 Compositions of the present invention three preparations

[0017] The present invention (32 parts of Poria cocos, 30 parts of Semen Plantaginis, 30 parts of Honeysuckle, 15 parts of Achyranthes bidentata, 10 parts of Zihua Diding) grinds the decoction pieces of the traditional Chinese medicine in the prescription into a powder, and takes the raw material powder according to the weight ratio of the above drug prescription components, Mix well, add water to soak for 1 hour, cook twice in a steam jacketed pot, combine the second filtrate, let it stand for 10-12 hours, take the supernatant and decoct and concentrate it into a decoction according to the amount of each dose of raw medicine , divided into bottles, and steam sterilized.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating and preventing diabetes lower limb vasculopathy. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight of 30-50 parts of poria cocos, 30 parts of semen plantaginis, 30-90 parts of flos lonicerae, 15 parts of radix achyranthis bidentatae and 10-30 parts ofherba violae. The invention further provides an application of the traditional Chinese medicine composition. Pharmacological and pharmacodynamic experiments prove that the traditional Chinese medicine composition can relieve the degree of lower limb vasculopathy of rats with diabetes; the blood coagulation function of rats with diabetes can be improved; and the inflammation condition of rats withdiabetes can be improved. Therefore, the compound can be used for preparing medicines for preventing and treating diseases related to diabetes lower limb vasculopathy. The extract or the compositionis simple in preparation method and low in cost, and a new medicine source is provided for preventing and treating diseases related to diabetes lower limb vasculopathy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating and preventing diabetic lower extremity vascular disease and its application. Background technique [0002] Diabetic lower extremity vascular disease is a common complication of diabetes. Lower extremity vascular disease mainly refers to lower extremity arterial disease, which is a component of peripheral arterial disease, manifested as stenosis or occlusion of lower extremity arteries. The risk of lower extremity arterial disease in diabetic patients is significantly higher than that in non-diabetic patients, and the onset age of lower extremity vascular disease is earlier, the condition is more serious, the lesion is more extensive, and the prognosis is worse. Arterial lesions of the lower extremities have common pathological mechanisms with arterial thrombotic diseases such as coronary artery disease...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61P3/10A61P9/14
CPCA61K36/076A61K36/21A61K36/355A61K36/68A61K36/86A61P3/10A61P9/14A61K2300/00
Inventor 王燕张云凤陆艳严怡婷侯波任子彦王子澄
Owner SHANGHAI PUTUO DISTRICT LIQUN HOSPITAL
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