Respiratory virus sample collection and detection integrated device

Abstract

The invention provides a respiratory virus sample collection and detection integrated device. A detection card is arranged on a wearing device, droplets are collected by protective equipment to be used as a sample for direct detection, protection is integrated with sample collection and detection, and viruses in the droplet sample can be automatically detected; manual throat swab sampling and detection operation is not needed, so on the one hand, a large amount of manpower and material resources can be saved, and meanwhile, the detection speed is remarkably increased; on the other hand, directcontact between medical staff and the droplets of the patient is effectively reduced, the mask can also be used as a common mask for isolating the droplets in the sampling detection process, and theinfection risk in the sampling process is greatly reduced. The device is suitable for rapid and efficient diagnosis of a large number of to-be-detected personnel, is especially suitable for rapid screening of a large number of suspected cases and closely contacted persons of definite cases, and can effectively relieve the pressure of detection and diagnosis work.

Description

technical field [0001] The invention belongs to the technical field of pathogen detection, in particular to an integrated device for collecting and detecting respiratory virus samples. Background technique [0002] With the increase in population size and density, the risk of large-scale outbreaks of epidemic infectious diseases is also increasing. Airborne transmission is the main route of transmission of epidemic respiratory diseases. Timely, rapid, accurate, simple, low-cost and high-throughput diagnosis of infected persons is the key to controlling the outbreak. However, it is not easy to do this. The transmission of epidemic respiratory diseases often has the following problems: [0003] ① Strong concealment: Many infected people have no obvious symptoms in the early stage, but they are still highly contagious. After they enter populated areas, they tend to cause widespread infection. How to find and diagnose such patients, there is no effective method at present; ...

AI Technical Summary

Problems solved by technology

[0003] ① Strong concealment: Many infected people have no obvious symptoms in the early stage, but they are still highly contagious

How to find and diagnose such patients, there is no effective method at present;

[0004] ②The speed of diagnosis is slow: for the newly discovered virus, since there is no corresponding antibody, only nucleic acid detection can be carried out, but the sensitivity of nucleic acid detection is low, and the false negative rate is high. Some patients even need multiple tests to be confirmed as positive. Significantly delayed diagnosis;

[0005] ③ It is difficult to determine the sampling site: the distribution of the new virus in the patient's body has not been fully grasped, so it is difficult to achieve accurate sampling, and the accuracy of the sampling site is directly related to the reliability of the test results

For example, although it is known that the new coronavirus is concentrated in the lungs this time, the operation of alveolar lavage fluid is complicated and requires special equipment, making it difficult to perform high-throughput detection; methods such as throat swabs are simple and fast, but the virus collected Small amount, still has a high false negative rate

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