Rapid Gleason scoring system for prostate digital pathological image

A digital pathology, prostate technology, applied in the field of prostate cancer and medical imaging, can solve the problems of inability to meet the needs of prostate cancer pathological diagnosis, high subjectivity, complicated operation process, etc., to achieve accurate Gleason score reference and reduce errors.

Pending Publication Date: 2020-11-24
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  • Description
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Problems solved by technology

[0004] The technical problem to be solved by the present invention is: the traditional Gleason scoring method is highly subjective, the operation process is complex, and the task is heavy, which cannot meet the needs of pathological diagnosis of prostate cancer

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  • Rapid Gleason scoring system for prostate digital pathological image
  • Rapid Gleason scoring system for prostate digital pathological image
  • Rapid Gleason scoring system for prostate digital pathological image

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Embodiment Construction

[0028] Below in conjunction with specific embodiment, further illustrate the present invention. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In addition, it should be understood that after reading the teachings of the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms also fall within the scope defined by the appended claims of the present application.

[0029] A fast Gleason scoring system for prostate digital pathological images provided by the present invention includes a data preprocessing unit, a semantic segmentation network loaded with pre-trained weights, and a Gleason scoring unit.

[0030] The data preprocessing unit performs data preprocessing operations on the prostate digital pathology images, and realizes image standardization and normalization through format conv...

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Abstract

The invention provides a rapid Gleason scoring system for a prostate digital pathological image, and the system is characterized in that the system comprises a data preprocessing unit which is used for data preprocessing of the prostate digital pathological image; a pre-training weight loaded semantic segmentation network used for outputting a five-channel probability graph according to the patchslices output by the data preprocessing unit; and a Gleason scoring unit used for carrying out post-processing on the five-channel probability graph and then carrying out calculation by utilizing an ISUP grading rule to obtain a Gleason score of the prostate digital pathological image. According to the method, the deep neural network technology is combined with the characteristics of the prostatedigital pathological image, the Gleason score is rapidly and automatically analyzed and predicted, subjective judgment errors are reduced, and more accurate Gleason score reference is provided.

Description

technical field [0001] The invention relates to the technical fields of prostate cancer and medical imaging, in particular to a fast Gleason scoring system for digital pathological images of the prostate. Background technique [0002] Prostate cancer is the second most deadly malignancy in men, and while common, it tends to be non-aggressive, making it difficult for doctors to determine whether the cancer poses a high enough risk to a patient to warrant treatment, such as surgical removal of the prostate or radiation therapy. Gleason grading is an important method that helps us assess the risk of prostate cancer patients. It uses a microscope to look at slides and grades the cancer cells based on how similar the sample is to a normal prostate. [0003] Although the clinical significance of Gleason grading of prostate cancer has been widely recognized, the operation process is very complicated and subjective. In addition, there is still a shortage of professionally trained ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00G06T7/11G06T7/62G06T7/90G06K9/62G06N3/04G06N3/08
CPCG06T7/0012G06T7/11G06T7/62G06T7/90G06N3/08G06T2207/10072G06T2207/30081G06N3/045G06F18/23213G06F18/2415
Inventor 张敬谊丁偕王瑜刘全祥杨佐鹏刘鸣
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