Metabonomics pathway-based myocardial infarction early warning method

Abstract

The invention discloses a metabonomics pathway-based myocardial infarction early warning method. The method specifically comprises the following steps of S1, taking in 10 patients with qi deficiency and easy chest distress and urgent breath and 10 healthy and symptomatic healthy people, not intervening in the normal life of the healthy people, and taking salvia miltiorrhiza traditional Chinese medicine formula granules for the patients with qi deficiency; and S2, respectively carrying out morning fasting blood sample collection on the two groups of subjects before and after intervening, settling the collected blood for 1.5 hours, centrifuging for 10 minutes at the temperature of 5 DEG C, and sealing after centrifuging, so that the invention relates to the technical field of medicines. According to the metabonomics pathway-based myocardial infarction early warning method, the nuclear magnetic resonance technology is combined with multivariate statistics to analyze the content change ofserum potential markers related to myocardial infarction resistance of salvia miltiorrhiza, and then metabolic pathway analysis is performed on the potential markers, so early warning of myocardial infarction of a patient is facilitated; and research of medical researchers on disease mechanisms is facilitated.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an early warning method for myocardial infarction based on metabonomics pathway. Background technique [0002] Myocardial infarction, also known as myocardial infarction, refers to ischemic necrosis of the myocardium. On the basis of coronary artery disease, the blood flow of the coronary artery is sharply reduced or interrupted, causing severe and persistent acute ischemia in the corresponding myocardium, which eventually leads to Myocardial ischemic necrosis, patients with acute myocardial infarction often have persistent severe substernal pain, fever, increased white blood cell count, elevated serum myocardial enzymes, and electrocardiogram reflecting acute myocardial injury, ischemia and necrosis. A series of characteristic evolution, and may appear arrhythmia, shock or heart failure, is a severe type of acute coronary syndrome. [0003] The perturbation of early biochemica...

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides an early warning method for myocardial infarction based on the metabonomics pathway, which solves the problem of failing to analyze the content changes of serum potential markers related to the anti-myocardial infarction of Danshen, and then failing to analyze potential Metabolic pathway analysis of markers is not conducive to early warning of myocardial infarction in patients, and affects medical researchers' research on disease mechanisms