Metabonomics pathway-based myocardial infarction early warning method

An early warning and metabolomics technology, applied in the field of medicine, can solve problems affecting the study of disease mechanisms, early warning of unfavorable myocardial infarction, and inability to analyze metabolic pathways of potential markers

Inactive Publication Date: 2021-02-09
BINHAI IND TECH RES INST OF ZHEJIANG UNIV
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides an early warning method for myocardial infarction based on the metabonomics pathway, which solves the problem of failing to analyze the content changes of serum potential markers re

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0020] The embodiment of the present invention provides a technical solution: an early warning method for myocardial infarction based on metabonomics pathway. The present invention uses nuclear magnetic resonance technology combined with multivariate statistics to analyze the content changes of potential markers in the serum of Danshen anti-myocardial infarction, and then Metabolic pathway analysis of potential markers is conducive to early warning of myocardial infarction in patients and facilitates medical researchers' research on ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a metabonomics pathway-based myocardial infarction early warning method. The method specifically comprises the following steps of S1, taking in 10 patients with qi deficiency and easy chest distress and urgent breath and 10 healthy and symptomatic healthy people, not intervening in the normal life of the healthy people, and taking salvia miltiorrhiza traditional Chinese medicine formula granules for the patients with qi deficiency; and S2, respectively carrying out morning fasting blood sample collection on the two groups of subjects before and after intervening, settling the collected blood for 1.5 hours, centrifuging for 10 minutes at the temperature of 5 DEG C, and sealing after centrifuging, so that the invention relates to the technical field of medicines. According to the metabonomics pathway-based myocardial infarction early warning method, the nuclear magnetic resonance technology is combined with multivariate statistics to analyze the content change ofserum potential markers related to myocardial infarction resistance of salvia miltiorrhiza, and then metabolic pathway analysis is performed on the potential markers, so early warning of myocardial infarction of a patient is facilitated; and research of medical researchers on disease mechanisms is facilitated.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an early warning method for myocardial infarction based on metabonomics pathway. Background technique [0002] Myocardial infarction, also known as myocardial infarction, refers to ischemic necrosis of the myocardium. On the basis of coronary artery disease, the blood flow of the coronary artery is sharply reduced or interrupted, causing severe and persistent acute ischemia in the corresponding myocardium, which eventually leads to Myocardial ischemic necrosis, patients with acute myocardial infarction often have persistent severe substernal pain, fever, increased white blood cell count, elevated serum myocardial enzymes, and electrocardiogram reflecting acute myocardial injury, ischemia and necrosis. A series of characteristic evolution, and may appear arrhythmia, shock or heart failure, is a severe type of acute coronary syndrome. [0003] The perturbation of early biochemica...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G01N24/08
CPCG01N24/08
Inventor 凌雪峰
Owner BINHAI IND TECH RES INST OF ZHEJIANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap