Biodegradable magnetically controlled pva micromotor bracket and its preparation method and application
A product and medical technology, applied in drug delivery, pharmaceutical formulations, surgery, etc., can solve the problems of insufficient biocompatibility of vascular stents, reduced treatment effectiveness, vascular restenosis, etc., to inhibit adverse reactions of intimal hyperplasia, reduce Invasiveness and implantation risk, high biocompatibility effect
Active Publication Date: 2022-05-24
SUN YAT SEN UNIV
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Problems solved by technology
[0003] Vascular stent implantation is an effective medical intervention for the treatment of vascular stenosis-related diseases. However, in the prior art, vascular stents prepared from traditional materials have problems such as insufficient biocompatibility and the need to introduce additional shape expansion devices. Moreover, in order to ensure The accuracy of implantation requires highly invasive treatment methods, and the existence of these problems can easily cause restenosis and arterial damage, thereby reducing the effectiveness of treatment
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[0045] In order to make the invention purpose, technical solutions and technical effects of the present invention clearer, the present invention will be further described in detail below with reference to the specific embodiments. It should be understood that the specific embodiments described in this specification are only for explaining the present invention, rather than for limiting the present invention.
[0046] The experimental materials and reagents used, unless otherwise specified, are conventional consumables and reagents that can be obtained from commercial sources.
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Abstract
The invention discloses a biodegradable magnetically controlled PVA micro-motor support, a preparation method and an application thereof. The magnetically controlled PVA material is obtained by mixing and crosslinking polyvinyl alcohol, magnetic particles, a crosslinking agent, and water. The vascular stent prepared by using the material in the present invention can use ultrasound to trigger shape memory, and cooperate with the motion performance of the magnetic drive motor , can simplify the adjustment process of the material formula and the implantation process, control the movement of the stent in the body to reach the target position, without the need for fixed-point implantation, further reduce the invasiveness and implantation risk, and more meet the actual application requirements.
Description
technical field [0001] The invention belongs to the field of biological materials, and in particular relates to a biodegradable magnetron PVA micromotor support and a preparation method and application thereof. Background technique [0002] Micromotor is an artificial power device with excellent motion performance and precise navigation performance, and has broad application prospects in the field of biomedicine. Biocompatibility has important research significance. [0003] Vascular stent implantation is an effective medical intervention for treating diseases related to vascular stenosis. However, in the prior art, vascular stents prepared from traditional materials have problems such as insufficient biocompatibility and the need to introduce additional shape expansion devices. The accuracy of implantation requires highly invasive treatment methods, and the existence of these problems can easily lead to vascular restenosis and arterial injury, thereby reducing the effectiv...
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IPC IPC(8): A61L31/14A61L31/04A61L31/02C08J3/075C08J3/24C08L29/04C08K5/3492C08K3/22
CPCA61L31/145A61L31/048A61L31/14A61L31/028C08J3/075C08J3/24C08J2329/04C08K5/34922C08K2201/011C08K2003/2275C08K2201/01A61L2400/12A61L2400/16C08L29/04
Inventor 彭飞苏沛锋覃枫莹王珍
Owner SUN YAT SEN UNIV




