Application of pharmaceutical composition in preparation of medicine for preventing and/or treating thin endometrium or infertility

An endometrial and composition technology, which is applied in the directions of drug combination, drug delivery, plant/algae/fungus/moss components, etc., can solve the problems of complex treatment methods and high cost, and achieve excellent therapeutic effects.

Active Publication Date: 2021-09-03
陆华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this treatment method needs to give compound Xuanju Capsules and estrogen to the pa

Method used

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  • Application of pharmaceutical composition in preparation of medicine for preventing and/or treating thin endometrium or infertility
  • Application of pharmaceutical composition in preparation of medicine for preventing and/or treating thin endometrium or infertility
  • Application of pharmaceutical composition in preparation of medicine for preventing and/or treating thin endometrium or infertility

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0027] Recipe: Epimedium 10g, Drynaria drynaria 10g, Cistanche 10g.

[0028] Preparation method: take the above-mentioned herbal flavors, add water to decoct, decoct twice in total, add water 6 times (v / w, ml / g) of the raw medicinal materials each time, combine the two decoction liquids, concentrate to a thick extract (The relative density is about 1.2), and the dregs are dried and finely powdered, then mixed with the extract, and spray-dried into granules.

Embodiment 2

[0029] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0030] Recipe: Epimedium 7g, Drynaria 7g, Cistanche 7g.

[0031] Preparation method: take the above-mentioned herbs, add water to decoct, decoct twice in total, add water 8 times (v / w, ml / g) the amount of raw medicinal materials each time, combine two decoctions, concentrate to a thick extract (relative density is about 1.35), the dregs are dried and finely powdered, then mixed with the extract, spray-dried into granules.

Embodiment 3

[0032] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0033] Recipe: Epimedium 13g, Drynaria drynaria 13g, Cistanche 13g.

[0034] Preparation method: take the above-mentioned herbs, add water to decoct, decoct 2 times in total, add water 7 times (v / w, ml / g) the amount of raw medicinal materials each time, combine the two decoctions, concentrate to a thick extract (The relative density is about 1.3), and the dregs are dried and finely powdered, then mixed with the extract, and spray-dried into granules.

[0035] The beneficial effect of the pharmaceutical composition of the present invention is demonstrated by the following experimental examples.

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Abstract

The invention provides application of a pharmaceutical composition in preparation of a medicine for preventing and/or treating thin endometrium or infertility. The pharmaceutical composition is a preparation prepared from the following raw material medicines in parts by weight of 7-13 parts of herba epimedii, 7-13 parts of rhizoma drynariae and 7-13 parts of herba cistanche. Experiments prove that after the pharmaceutical composition provided by the invention is taken, the endometrial receptivity of a thin endometrial (kidney-yang deficiency syndrome) patient is remarkably improved, the endometrial thickness, the female progestational hormone level in the middle stage of corpus luteum and the endometrial blood supply of the patient are remarkably improved, and the total effective rate of treatment is up to 87.88%. The pharmaceutical composition provided by the invention is precise and appropriate in compatibility, and has a wide prospect in preparation of medicines for preventing and/or treating kidney-yang deficiency type thin endometrium and thin endometrial infertility.

Description

technical field [0001] The invention belongs to the field of pharmacy, and in particular relates to the use of a pharmaceutical composition in the preparation of medicines for preventing and / or treating thin endometrium or infertility. Background technique [0002] In 1995, the World Health Organization (WHO) found that the number of infertile couples in the world had reached 60-80 million. Therefore, WHO regards infertility as the world's third largest impact on human physical and mental health after cardiovascular diseases and tumor diseases. disease. At present, the incidence of infertility in the world is increasing year by year. According to incomplete statistics, the incidence of infertility in my country is 7-10% in recent years. Although the assisted reproductive technology (ART) of modern medicine has brought hope to the majority of infertility patients, studies have shown that about 2.4% of patients were forced to cancel or terminate ART due to the thin endometriu...

Claims

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Application Information

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IPC IPC(8): A61K36/64A61P15/08A61P15/00
CPCA61K36/296A61K36/126A61K36/64A61K9/0053A61P15/00A61P15/08A61K2300/00
Inventor 陆华刘芊辰
Owner 陆华
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