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Hyperspectral quantitative imaging cytometry system

A hyperspectral and cytometry technology, applied in optical radiation measurement, spectrometry/spectrophotometry/monochromator, spectrum investigation, etc., can solve problems such as slowness

Pending Publication Date: 2022-01-07
西托诺斯有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, like LSC, this method suffers from the same drawback as a very slow technique since the sample is "imaged" on a single pixel basis

Method used

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Embodiment Construction

[0106] 1-A to 1-E schematically illustrate a hyperspectral quantitative imaging cytometry system 100 according to the present invention.

[0107] The system 100 includes an observation region 104 that includes a sample holding portion 112 configured to hold one or more solid phase samples. In one embodiment, the sample holding portion is configured to hold at least one solid phase sample support, each support being adapted to accommodate a fixed sample, preferably a biological sample. These solid-phase sample supports can be of different materials (preferably, crystalline and light-transparent materials such as glass or plastic), and can have different shapes and sizes (for example, rectangular shapes (for example, microscope slides) piece)).

[0108] Biological samples can be of human, animal, fungal or plant origin and can be used alone or in combination with molecular markers.

[0109] Preferably, molecular markers are used to reveal components of the biological sample. ...

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Abstract

The present invention relates to hyperspectral detection of luminescence and, in particular, to the detection of luminescence from solid phase samples which are stimulated with radiation sources.

Description

technical field [0001] The present invention relates to the hyperspectral detection of luminescence and, in particular, to the detection of luminescence from solid-phase samples excited by a radiation source. Background technique [0002] The function of a biological tissue is the result of the synergy of its cellular components. Each of these cells exhibits a specific phenotype resulting from its interaction with the tissue environment, and any dysregulation of these mechanisms can lead to diseases such as cancer. Therefore, being able to analyze single-cell features in spatial context is critical to understanding how tissues work under normal and disease conditions and to aid in the development of effective therapeutics. [0003] The findings of disease affecting specific tissues may not always be apparent through traditional histological and morphological assessment. Certain structures and components of tissues may be morphologically similar but exhibit major difference...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/14G01J3/32G01J3/12G01J3/28G01N15/10
CPCG01N15/1429G01N2015/144G01J2003/1243G01J2003/2826G01N2015/1006G01J3/26G01J2003/1234G01J2003/123G01J2003/102G01J3/2823G01N15/1433G01J3/32
Inventor 荷西马里奥·特内拉莫尔加多阿尔瓦罗·罗德里格斯德拉加拉
Owner 西托诺斯有限公司
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