Preparation method for extracting lupeol-containing herbal medicine component from indigofera pseudotinctoria

Abstract

The invention discloses a preparation method for extracting a lupeol-containing herbal medicine component from indigofera pseudotinctoria. The indigofera pseudotinctoria is used as a raw material, an organic solvent is used for extracting the indigofera pseudotinctoria to obtain lupeol, the process is simple, the production cost is low, the extraction efficiency is high, and the lupeol has important pharmacological action as cyclotriterpenoid lupeane. The lupeol is separated and extracted from the indigofera pseudotinctoria and is used for inhibiting human breast cancer MCF-7 cells through an in-vitro test. The invention provides a method for developing new anti-breast cancer drugs by utilizing natural active substances of indigofera pseudotinctoria.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method for extracting lupeol from horse thorn and its application for inhibiting human breast cancer MCF-7 cells. Background technique [0002] Breast cancer is a malignant tumor in the glandular epithelial tissue of the breast. The difficulty of its clinical treatment is that it is difficult to detect in the early stage. It is difficult to completely remove the lesion by surgical resection, and most patients are prone to recurrence. Although chemotherapy drugs are widely used in the treatment of breast cancer, the impact of their side effects and durability on the treatment process and efficacy of patients cannot be ignored. Therefore, it is an inevitable trend to search for therapeutic drugs with lower toxicity. Natural products are an important source of antitumor drugs. Triterpenoids are important secondary metabolites in plants and have a wide ran...

AI Technical Summary

Problems solved by technology

[0002] Breast cancer is a malignant tumor in the glandular epithelial tissue of the breast. The difficulty of its clinical treatment is that it is difficult to detect in the early stage. It is late when it is discovered. It is difficult to completely remove the lesion by surgical resection, and most patients are prone to recurrence

Although chemotherapy drugs are widely used in the treatment of breast cancer, the impact of their side effects and durability on the treatment process and efficacy of patients cannot be ignored

Images