Traditional Chinese medicine composition for treating female gouty arthritis as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for treating female gouty arthritis as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 4-5 parts of aspongopus, 6-7 parts of fenugreek, 6-7 parts of radix echinopsis, 10-15 parts of commelina communis, 0.1-1 part of resina toxicodendri and 4-5 parts of amomum tsao-ko. The traditional Chinese medicine composition has the basic effects of warming kidney and expelling dampness, removing heat and diminishing swelling, and removing blood stasis and resolving stagnation. Experiments prove that the traditional Chinese medicine composition can improve the joint swelling degree, the joint inflammation index and the related inflammatory mediator content of the toe of a female gouty arthritis model mouse, and can also improve the Toll-like receptor-4 protein and gene basic expression level of the toe of the model mouse; the traditional Chinese medicine composition has no influence on visceral organ indexes and body weight of important organs of a model mouse, so that the traditional Chinese medicine composition disclosed by the invention is effective for treating the female gouty arthritis and has no side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to a traditional Chinese medicine composition for treating female gouty arthritis, its preparation method and application. The invention belongs to the technical field of traditional Chinese medicine research. Background technique [0002] Gouty arthritis (Gouty arthritis) is common in the body's joint capsule and its cartilage, such as the first metatarsophalangeal joint of the body's lower limbs (Hase R, Kurata R, Ishida K, et al.Acute Gouty Arthritis During Favipiravir Treatment for Coronavirus Disease 2019[ J]. Intern Med, 2020, 59(18): 2327-2329.), can occur in women, mostly related to social factors, genetic factors, stress factors, psychological factors and dietary factors (Fattori V, Staurengo-Ferrari L, Zaninelli TH, et al. IL-33enhances macrophage release of IL-1beta and promotes pain and inflammation in goutyarthriti...

AI Technical Summary

Problems solved by technology

Various symptoms are not obvious during the asymptomatic interval, but it is easy to evolve into the chronic arthritis period

Images