Colon treatment methods and devices

A product, ultrasound technology, applied in treatment, sigmoidoscopy, ultrasound therapy, etc., can solve problems such as ineffective biofilm removal and low efficiency of ultrasound devices

Pending Publication Date: 2022-04-08
托马斯·朱利叶斯·波洛迪 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This shortcoming makes various ultrasound devices of this type ineffective when attempting to treat large tissue surface areas (e.g., the wall of the large intestine)
In addition to ultrasonic damage to biofilms, liquid jets delivered to the intestinal lumen have been used to enhance biofilm removal, but not efficiently

Method used

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  • Colon treatment methods and devices
  • Colon treatment methods and devices
  • Colon treatment methods and devices

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Embodiment Construction

[0153] In alternative embodiments, there are provided articles of manufacture, uses and methods for removing and / or disrupting gastric luminal (e.g., colon) biofilms, and including for treating or ameliorating biofilm-associated diseases, disorders and luminal infections, and Apparatus and apparatus for removing and / or disrupting gastric luminal biofilms and for practicing the methods provided herein. In alternative embodiments, devices and apparatus and methods for enhancing dissolution or disruption of biofilms are provided, wherein in alternative embodiments, the biofilm comprises a gastric cavity 'non-stirring layer', an adhesive layer, or a gastric cavity mucus layer ; or the biofilm comprises a matrix or DNA-containing layer, or alternatively the biofilm comprises a polysaccharide periluminal layer.

[0154] In alternative embodiments, articles of manufacture, uses and methods for removing or treating infected biofilms, including infected biofilms in the gastrointestinal...

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Abstract

Products of manufacture and methods for in situ removal and / or disruption of biofilms, such as gastral cavity biofilms, and for treating or ameliorating biofilm-related diseases, infections and conditions, including gastrointestinal (GI) cavity infections, are provided. Devices and apparatus for in situ removal, disruption and / or disruption of biofilms, such as gastral cavity biofilms, and methods of using the same are provided. In alternative embodiments, devices and apparatus and methods are provided for enhancing a biofilm solubilizing or disrupting agent, or for administering a biofilm solubilizing or disrupting agent, where in alternative embodiments, a biofilm comprises a gastral cavity'non-agitation layer ', an adhesion layer, or a gastral cavity mucus layer; or the biofilm comprises a matrix or a DNA-containing layer, or alternatively, the biofilm comprises a polysaccharide gastral peripheral layer.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US 62 / 882,412, filed August 2, 2019, the entire disclosure of which is incorporated herein by cross-reference. technical field [0003] The present invention relates generally to gastroenterology and colon microbiome biology and transplantation. Provided are methods for removing and / or disrupting biofilms in situ, such as gastric cavity biofilms, and for treating or ameliorating biofilm-related diseases, infections and conditions, including gastrointestinal (GI) cavity infections, such as fecal microbial bacteria Articles of manufacture and methods of preparation for fecal microbiotatransplantation (FMT). Devices and devices for in situ removal, disruption and / or destruction of biofilms, such as gastric luminal biofilms, and methods of using them are provided. In alternative embodiments, devices and apparatus and methods for enhancing biofilm dissolving or disrupting agents, or for ...

Claims

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Application Information

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IPC IPC(8): A61B17/22A61B18/08A61B18/14A61L2/025A61B8/00
CPCA61B17/22004A61B1/00066A61N2007/0078A61B1/005A61B2560/0462A61N2007/0039A61B2560/0242A61B1/273A61B2017/22028A61N2007/0043A61B2562/0271A61B2017/22021A61N7/00A61B1/00133A61B17/2202A61B2560/0468A61B1/00135A61B8/12A61B2017/22062A61N7/022A61B2017/00084A61B90/361A61B2017/00526A61N2007/0095A61B2217/005A61B2217/007A61B1/015A61B1/05A61B1/06A61B1/0011A61B1/053A61B1/00094A61B1/00097A61B2017/320012A61B2017/22079A61B2017/22092A61B2017/22082A61B1/31A61B2017/00296
Inventor 托马斯·朱利叶斯·波洛迪安东尼·米利斯
Owner 托马斯·朱利叶斯·波洛迪
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