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Medicine for treating vascular dementia and preparing method

A technology for vascular dementia and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problem of lack of specific drugs for vascular dementia, and achieve a significant therapeutic effect

Inactive Publication Date: 2006-03-08
QIANFOSHAN HOSPITAL OF SHANDONG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine lacks specific drugs with good effect on the treatment of vascular dementia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0091] Take raw material (by weight) and make by following proportioning ratio:

[0092] 90 parts of Polygonum multiflorum, 70 parts of Astragalus membranaceus, 10 parts of Salvia miltiorrhiza, 9 parts of Chuanxiong, 25 parts of Shichangpu, 25 parts of Yizhiren, 1 part of total flavonoids of Ginkgo biloba, 3 parts of earthworm, 1 part of leech, 20 parts of Gastrodia elata.

[0093] The production method is as follows:

[0094] a. Extract Polygonum multiflorum, Radix Astragali, Salvia Miltiorrhiza and Rhizoma Chuanxiong by ethanol in proportion;

[0095] b. Decoct Shichangpu and Yizhiren according to the proportion, and then filter;

[0096] c. the filtrate in the b step is combined with the ethanol extract in the a step, concentrated to a thick paste, dried under reduced pressure, and pulverized into extract powder;

[0097] d. Pulverize Gastrodia elata, leech, and earthworm in proportion, then mix the extract powder, gastrodia elata powder, leech powder, earthworm powder an...

Embodiment 2

[0098] Embodiment 2: take raw material (by weight) and make by following proportioning ratio:

[0099] 60 parts of Polygonum multiflorum, 40 parts of Astragalus membranaceus, 30 parts of Salvia miltiorrhiza, 20 parts of Chuanxiong, 15 parts of Shichangpu, 15 parts of Yizhiren, 5 parts of total flavonoids of Ginkgo biloba, 15 parts of earthworm, 5 parts of leech, and 12 parts of Gastrodia elata.

[0100] The production method is as follows:

[0101] a. Extract Polygonum multiflorum, Radix Astragali, Salvia Miltiorrhiza and Rhizoma Chuanxiong by ethanol in proportion;

[0102] b. Decoct Shichangpu and Yizhiren according to the proportion, and then filter;

[0103] c. the filtrate in the b step is combined with the ethanol extract in the a step, concentrated to a thick paste, dried under reduced pressure, and pulverized into extract powder;

[0104] d. Pulverize Gastrodia elata, leech, and earthworm in proportion, then mix the extract powder, gastrodia elata powder, leech powde...

Embodiment 3

[0105] Embodiment 3: take raw material (by weight) and make by following proportioning ratio:

[0106] 25 parts of Polygonum multiflorum, 14 parts of Astragalus membranaceus, 50 parts of Salvia miltiorrhiza, 35 parts of Chuanxiong, 4 parts of Shichangpu, 4 parts of Yizhiren, 10 parts of total flavonoids of Ginkgo biloba, 30 parts of earthworm, 10 parts of leeches, and 3 parts of Gastrodia elata.

[0107] The production method is as follows:

[0108] a. Extract Polygonum multiflorum, Radix Astragali, Salvia Miltiorrhiza and Rhizoma Chuanxiong by ethanol in proportion;

[0109] b. Decoct Shichangpu and Yizhiren according to the proportion, and then filter;

[0110] c. the filtrate in the b step is combined with the ethanol extract in the a step, concentrated to a thick paste, dried under reduced pressure, and pulverized into extract powder;

[0111] d. Pulverize Gastrodia elata, leech, and earthworm in proportion, then mix the extract powder, gastrodia elata powder, leech powd...

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Abstract

The present invention relates to a medicine for curing vascular dementia. Said medicine is made up by using the Chinese medicinal materials of flowery knotweed root, astragalus root, salvia root, ligusticum root, acorus root, alpinia fruit, ginkgo leaf total flavone, earthworm, leech and gastrodia root as raw material through a certain preparation process. Said invention also provides the concrete steps of said preparation process, and said medicine can be made into the dosage forms of capsule, etc.

Description

technical field [0001] The invention relates to a medicine and a preparation method thereof, in particular to a medicine for treating vascular dementia with Chinese herbal medicine as a raw material and a preparation method thereof. Background technique [0002] We know that vascular dementia (VD) is a clinical syndrome of intelligence and cognitive dysfunction caused by cerebrovascular diseases. VD accounts for 15-20% of all dementias in western countries, and the proportion is relatively high in my country and Japan. It is the second most common dementia after Alzheimer's disease. Timely and effective treatment of this disease can significantly improve the quality of life of patients and reduce the burden on families and society. At present, there is a lack of specific drugs with good effect in the treatment of vascular dementia by western medicine. Contents of the invention [0003] In order to overcome the above deficiencies in the prior art, the present invention pr...

Claims

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Application Information

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IPC IPC(8): A61K36/906A61K36/16A61K35/64A61K9/48A61P25/28
Inventor 李长生刘逢芹李军
Owner QIANFOSHAN HOSPITAL OF SHANDONG
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