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Soft capsule preparation with ultramicro powder and preparation method thereof

The technology of a soft capsule preparation and salvia miltiorrhiza is applied in the field of traditional Chinese medicine soft capsule preparation and its preparation, and can solve the problems of poor absorption, low bioavailability, long disintegration time of Guanxinjing capsule, etc.

Inactive Publication Date: 2006-10-04
海口绿科南药研究开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The disintegration time of Guanxinjing Capsules is long, and because the capsules contain raw medicinal powder, the absorption is poor and the bioavailability is low, which affects the curative effect of Guanxinjing Capsules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0037] Superfinely pulverize 31.25g Chuanxiong, 12.5g Panax notoginseng, 6.25g ginseng; take 62.5g salvia miltiorrhiza, 31.25g red peony root, 31.25g safflower, 31.25g Polygonatum odoratum, add 15 times the amount of water to decoct twice, each time 2 hours, the filtrates were combined, the filtrates were concentrated to a thick paste, dried under reduced pressure, and ultrafinely pulverized; together with 2.5g styrax and 0.625g borneol, they were added to 300g diluent (15g beeswax was added to 285g soybean oil), and mixed to make a medicinal solution . Get 500g of gelatin, 150g of glycerin and 500g of water to make glue. Utilize pressing method, make 1000 soft capsules, get final product.

preparation example 2

[0039] Superfinely pulverize 41.7g Rhizoma Chuanxiong, 16.7g Panax notoginseng, and 8.3g ginseng; take 83.3g salvia miltiorrhiza, 41.7g red peony root, 41.7g safflower, 41.7g Polygonatum odoratum, add 15 times the amount of water to decoct twice, each time 2 hours, the combined filtrate, the filtrate was concentrated to a thick paste, and after drying under reduced pressure, it was ultrafinely pulverized; together with 3.3g styrax and 0.8g borneol, add in 350g diluent (add 10g palm oil to 340g olive oil), mix well, and make medicine liquid. Get 450g of gelatin, 200g of glycerin and 450g of water to make glue. Utilize pressing method, make 1000 soft capsules, get final product.

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PUM

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Abstract

The invention discloses a soft capsule preparation and its preparing process, wherein the capsule is prepared from root of red rooted saliva, radix paeoniae rubrathe, Ligusticum wallichii, safflower, fragrant solomonseal rhizome, notoginseng, gen-seng, liquidambar orientalis mill, and baras camphor through the steps of disintegrating and water extracting.

Description

technical field [0001] The invention relates to a traditional Chinese medicine soft capsule preparation and a preparation method thereof. The preparation is composed of salvia miltiorrhiza, red peony root, chuanxiong, safflower, polygonatum polygonatum, notoginseng, ginseng, styrax and borneol. Background technique [0002] Guanxinjing Capsule (WS-10594-(ZD-0594)-2002) is used in clinical practice, and is a compound preparation of traditional Chinese medicine. It has the functions of promoting blood circulation and removing blood stasis, nourishing qi and unblocking the meridians, and is clinically used for chest pain, shortness of breath, palpitations and coronary heart disease caused by qi deficiency and blood stasis. [0003] The disintegration time of Guanxinjing Capsules is long, and because the capsules contain raw medicinal material powder, the absorption is poor and the bioavailability is low, which affects the curative effect of Guanxinjing Capsules. [0004] The p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/48A61P9/10
Inventor 滕厚雷
Owner 海口绿科南药研究开发有限公司
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