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Extractive of volatile oil of datura flower, and application

A technology of volatile oil and jasmine flower, applied in the application field of medicine, can solve problems such as tumor treatment application that has not yet been seen

Inactive Publication Date: 2007-05-09
卡南吉医药科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The domestic and foreign scholars' research on Dajinhua mainly focuses on its alkaloid components, so the reports on the pharmacological activity and clinical application of Dajinhua are also basically focused on the application of asthma, cough, analgesia and antispasmodic. , has not seen its application in tumor therapy

Method used

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  • Extractive of volatile oil of datura flower, and application
  • Extractive of volatile oil of datura flower, and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1 prepares daphnia volatile oil extract

[0040] Add 4000 mL of water to 500 g of datura, steam distillation for 5 hours, collect the distilled volatile oil with a volatile oil collector, separate and remove the water layer to obtain 1.1 g of datura volatile oil extract.

Embodiment 2

[0041] Embodiment 2 prepares datura volatile oil extract

[0042] Add 5000 mL of water to 500 g of Dajinhua, add 5000 mL of water, steam distill for 6 hours, collect the distilled volatile oil and the water layer containing volatile oil with a volatile oil collector, add diethyl ether for extraction three times, adding 10 mL each time, combine the diethyl ether layers, and evaporate the diethyl ether to obtain Datura volatile oil extract 1.2g.

Embodiment 3

[0043] Embodiment 3 prepares daphnia volatile oil extract

[0044] Crush daphnia flowers and put them into an extraction kettle for supercritical carbon dioxide extraction. The extraction temperature is 35°C, the extraction pressure is 12Mpa, the CO2 flow rate is 5L / hr per kilogram of crude drug, and it is extracted for 240 minutes through the separation tank, and the pressure of the separation tank is 6Mpa. , temperature 40°C, the orange liquid obtained by the separator is the volatile oil extract of daphnia japonica.

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Abstract

A volatile oil of daturae flower used to prepare the medicines for treating tumor is prepared from daturae flower through supercritical CO2 extracting or distilling.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine. In particular, it relates to an extract of daphnia flora volatile oil and its application in the preparation of medicines for treating tumors. Background technique [0002] Tumors are a common condition. According to statistics, according to WHO statistics, there are more than 10 million new cancer cases in the world every year, about 60% of them die, and more than 20 million patients need care. Compared with 1990, its morbidity and mortality have increased by more than 20%. Lung cancer is the cancer with the highest incidence rate in the world today, ranking first in the incidence and death of common cancers; the second is breast cancer; the third is colorectal cancer; the fourth is gastric cancer; the fifth is liver cancer. In Asia, the incidence of cancer in China is much higher than that in Japan, South Asia and West Asia. [0003] Traditional cancer treatments are ma...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61P35/00
Inventor 王晓川吴威巍王作鹏
Owner 卡南吉医药科技(上海)有限公司
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