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a shunt and disc technology, applied in the field of u-shaped disc shunt and delivery device, can solve the problems of low back, reduced efficiency, and limited diffusion of nutrients through the calcified endplate, and achieve the effect of reducing friction
Inactive Publication Date: 2007-06-21
ALEEVE MEDICAL INC
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[0059]FIG. 10 shows a cross section of the triangular needle 101 and disc shunt 126 extending from the ...
Problems solved by technology
Low back pain is a leading cause of disability and lost productivity.
When the endplate is obliterated by bone, diffusion of nutrients through the calcified endplate is greatly limited.
In addition to hindering the diffusion of nutrients, calcified endplates further limit the permeation of oxygen into the disc.
As a result, the sulfated glycosaminoglycan concentration decreases, leading to...
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[0081] Disc shunt 126 is a flexible and semi-permeable conduit transporting nutrients, waste and oxygen between bodily circulation and the avascular disc 100. The disc shunt 126 is bent into a U- or V-configuration. The lengths of the bent portions do not have to be equal. One end of the U-shaped shunt 126 is inserted into the lumen 269 of a thin needle 101 while the other end of the U-shaped shunt 126 is draped over the outside wall of the thin needle 101, as shown in FIG. 1.
[0082] Since diffusion of nutrients can only penetrate up to 1 cm into the annular layers, the U-shaped disc shunt 126 is delivered deep into the annulus by puncturing the disc 100 with the needle 101, as shown in FIG. 2. As the needle 101 punctures into the disc 100, the outside strand of the U-shaped shunt 126 is pulled, dragged and tightly pressed against the annular layers beside the outside wall of the needle 101 through a small puncture hole. During needle 101 withdrawal, the contact friction between the...
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Abstract
The intervertebral disc contains no blood vessels. Nutrients and waste are diffused mainly through adjacent vertebral bodies. As we age, calcified layers form between the disc and vertebral bodies, blocking diffusion. The disc begins to starve and flatten. The weight shifts abnormally from disc to the facet joints causing strain and back pain. Under anaerobic conditions, lactic acid is produced causing acidic irritation and unspecific pain. A U-shaped disc shunt is delivered into and sealed within the degenerated disc simply by needle puncturing and withdrawal, to draw nutrients from bodily circulation into the avascular disc. A continual supply of nutrients increases biosynthesis of the water-retaining sulfated glycosaminoglycans, hence swelling pressure within the disc. The weight is re-shifted from the facet joints to the regenerated disc, alleviating back pain. With oxygen transported through the shunt, anaerobic production of lactic acid is minimized. In addition, the residual lactic acid is expelled through the U-shaped shunt during disc compression into bodily circulation to alleviate unspecific pain.
Description
CROSS-REFERENCES TO OTHER APPLICATIONS [0001] This application is a continuation-in-part of U.S. patent application Ser. No. 11 / 630,706, filed on Dec. 20, 2006, which is a National Stage Application of PCT / US2005 / 022749 filed Jun. 22, 2005, which claimed priority of U.S. Provisional Applications No. 60 / 582,228 filed on Jun. 22, 2004; 60 / 587,837 filed on Jul. 14, 2004; 60 / 660,120 filed on Mar. 8, 2005. [0002] This application is also a continuation-in-part of U.S. patent application Ser. No. 10 / 555,895, filed on Nov. 4, 2005, which is a National Stage Application of PCT / US2004 / 14368, filed on May 7, 2004, which claimed priority of U.S. Provisional Applications No. 60 / 468,770, filed on May 7, 2003; 60 / 480,057, filed on Jun. 20, 2003; 60 / 503,553, filed on Sep. 16, 2003; 60 / 529,065, filed on Dec. 12, 2003. [0003] This application claims priority of U.S. Provisional Applications No. 60 / 765,147, filed on Feb. 4, 2006; 60 / 784,631 filed on Mar. 22, 2006; 60 / 788,936 filed on Apr. 4, 2006.FIE...
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