Systems and methods for treating superficial venous malformations like spider veins
a technology of spider veins and systems, applied in the field of systems and methods for treating superficial vein malformations like spider veins, can solve problems such as localized injury to the inner wall of the vein, and achieve the effects of eliminating side effects such as bruising, burning, skin discoloration, and high cos
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[0075] The superficial venous anatomy of the ears of New Zealand White Rabbits were treated by injecting light-reactive agent LS11 (Talaporfin Sodium) in doses selected to approximate a human dose, and thereafter exposing the superficial venous anatomy to light at a wavelength of 664 nm in dose periods ranging from 8 to 12 minutes. Visible alterations in the superficial venous anatomy due to shrinkage of veins in the treated regions were observed.
[0076] New Zealand Rabbits were chosen because of their large ears having easily identifiable superficial venous anatomy (as FIG. 19 shows). A total of twelve rabbits were treated. Each rabbit (weighing approximately six pounds) was intravaneously sedated for approximately 25 minutes using Ketamine and secured to a treatment table before being treated. The ears were shaved clean of hair and skin prepped with alcohol.
[0077] LS11 (Talaporfin Sodium, from Light Sciences Oncology, Inc.) was selected as the light reactive agent 14. As FIG. 19 ...
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