2 results about "Sodium edetate" patented technology

A method for producing an adhesive layer composition for producing a cooling sheet including a backing layer, an adhesive layer, and a liner layer, the method comprising the step of:mixing a composition to be mixed containing water, an alum, sodium edetate, a polyacrylic acid, and a neutralized polyacrylic acid such that a mixing temperature becomes 5 to 23° C., to obtain an adhesive layer composition, whereinin the composition to be mixed,a content of the water is 69 to 938.24% by mass relative to a total mass of the composition to be mixed,a content of the alum is 0.18 to 0.42% by mass relative to the total mass of the composition to be mixed,a content of the sodium edetate is 0.08 to 0.18% by mass relative to the total mass of the composition to be mixed, anda mass ratio between the content of the alum and the content of the sodium edetate (the content of the alum: the content of the sodium edetate) is 1:1 to 5.25:1.

The present invention relates to a pharmaceutical formulation with improved stability, comprising: an endoglycosidase hydrolase; a phosphate-based buffer; a stabilizer comprising sodium chloride, sodium edetate, and calcium chloride; and a nonionic surfactant.