4 results about "Tissue Distributions" patented technology

The invention relates to a method for predicting absorption in medical imaging by providing (S1) an absorption model based on at least one physiological parameter and a tissue distribution, providing (S3) a group of patient data, translating (S4) the group of patient data into a statistical distribution of at least the physiological parameter and determining (S5) a statistical distribution of absorption values ​​for the group with the absorption model as a function of the statistical distribution of the physiological parameter.

This invention discloses a mouse experimental method for detecting the tissue distribution of exogenous oxytocin, belonging to the field of biotechnology. Specifically, oxytocin is injected into or nasally sprayed into oxytocin knockout mice, and body tissues, including but not limited to brain tissue, mammary gland tissue, blood, heart tissue, uterine tissue, bone tissue, and muscle tissue, are collected at different time points. The tissue distribution and content of oxytocin are then detected using liquid chromatography-mass spectrometry (LC-MS / MS). This experimental method allows for a wider range of experimental samples, not just focusing on brain tissue and blood; it also has higher sensitivity and stronger specificity; and by utilizing oxytocin gene knockout mice, it eliminates the influence of endogenous oxytocin, providing certain assistance for subsequent animal experiments and clinical research on oxytocin.

The invention relates to a method for predicting absorption in medical imaging by providing (S1) an absorption model that is based on at least one physiological parameter and a tissue distribution, providing (S3) a group of patient data, translating (S4) the group of patient data into a statistical distribution of at least the physiological parameter and determining (S5) a statistical distribution of absorption values for the group with the absorption model in dependence upon the statistical distribution of the physiological parameter.

The application provides a sequence composition and a kit for detecting tissue distribution and / or expression level of an AAV vector drug.The sequence composition for detecting tissue distribution and / or expression level of the AAV vector drug provided by the application comprises a first forward primer as shown in SEQ ID NO:1, a first reverse primer as shown in SEQ ID NO:2 and a first probe as shown in SEQ ID NO:4.The sequence composition and the kit provided by the application have the remarkable advantages of being universal, efficient, specific, accurate, sensitive and the like in application, and provide a more optimal solution for detection and research in the related field.