The invention relates to a traditional Chinese medicine preparation for treating thrombocytopenic purpura. The traditional Chinese medicine preparation comprises pokeberry roots, hairyvein agrimony, indigo naturalis, lithospermum, radix sanguisorbae, rheum officinale, codonopsis pilosula, donkey-hide gelatin, carthamus tinctorius, fruit of purpleflower holly, eclipta alba, rhizoma polygonati, madder, cortex lycii radicis, cimicifuga foetida, cicada slough, fructus cnidii and stiff silkworms. The traditional Chinese medicine preparation can directly act on blood vessels and viscera, can treat both symptoms and root causes, has functions of conditioning and regulating yin and yang of spleens and lungs, inhibiting growth of megakaryocyte, promoting hematopoiesis, stimulating thrombocytopoiesis, substantially removing factors damaging blood platelet, alleviating damage of blood platelet, improving blood circulation, and recovering self-regulation of blood systems and immune systems, and can be used for thoroughly eliminating symptoms of cold intolerance, fever, cutaneous pruritus, ecchymosis and the like, and alleviating endocrine function disorder to achieve balance of ying and yang, so that the purpose of thoroughly healing thrombocytopenic purpura is ultimately achieved.