Injection type tissue engineering bone renovation material and construct method thereof

Abstract

The invention relates to an injection organism repair material and relative production. Wherein, it comprises carrier support and seed cell adhered on the carrier support to form skeleton three-dimension structure and biological active composite; and it uses the injection chitose-beta-tricalcium phosphate composite as carrier support to couple seed cell; the seed cell is bone marrow substrate stem cell. The test has proved that the chitose-beta-tricalcium phosphate composite has better compatibility with BMSCs.

Description

technical field

[0001] The invention belongs to the technical field of constructing artificial organs by tissue engineering method in biomedical engineering, and in particular relates to an injection-type tissue engineering bone and a construction method thereof. Background technique

[0002] At present, tissue engineered bone is mostly constructed as a model in which the scaffold material is loaded with cell growth factors and then compounded with seed cells. The selection of scaffold materials and growth factors is the focus of tissue engineering research. Scaffold materials, as seed cell carriers, have the functions of loading cells and slowing the release of growth factors. At present, most commonly used scaffold materials are solid materials, which have achieved remarkable results in the construction of tissue engineered bone. However, there are also defects such as difficulty in shaping, complex operation of loading growth factors and seed cells, low loading rate, and...

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