Amitraz compositions

A composition, the technology of three sub-mite, applied in the direction of acaricide, animal repellent, plant growth regulator, etc., can solve the problems of chemical instability and so on

Inactive Publication Date: 2007-09-12
WYETH LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, Trimite is chemically unstable in the presence of solvents with reactive hydroxyl groups such as alcohols, glycols, water, and the like

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0031] Preparation

[0032] The following solvents were introduced sequentially into a jacketed vessel at 25°C with stirring. N,N-diethyl-m-toluamide, dimethyl sulfoxide, eucalyptol, 1-methoxy-2-propyl acetate and γ-caprolactone. Slowly treat this solvent mixture with R-28153 and Trimite; continue to stir until dissolution is complete. The resulting solution was passed through a platen of activated 4A molecular sieves.

example 2

[0034] Preparation of ectoparasite-killing composition

[0035] C

[0036] γ-caprolactone

example 3

[0038] Preparation of ectoparasite-killing composition

[0039] E

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PUM

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Abstract

The present invention provides a stable composition which comprises a non-hydroxyl-group-containing solvent mixture comprising N,N-diethyl-m-toluamide and -hexalactone, optionally with dimethyl sulfoxide, eucalyptol and 1-methoxy-2-propyl acetate; and an effective amount of each of amitraz and at least one additional parasiticidal compound, such as R-28153. Said composition allows for high concentrations of a mixture of parasiticidal agents in a single application and is useful for treating and controlling parasiticidal infection and infestation in a homeothermic animal.

Description

technical field [0001] The present invention relates to triamyrine compositions, and more particularly, to triymite compositions in a hydroxyl-free solvent mixture, methods of using them and methods of preparing them. Background technique [0002] Sanya mite is a valuable veterinary drug product, which can effectively control many strains of ticks that are resistant to other chemical acaricides. It also has sufficient persistence on hair and wool to control all stages of parasitic ticks. The unique repelling action of the three submite can cause the tick to quickly remove the mouthparts from the host animal and shed it. Effective tick control combined with effective ecto- or endo-parasite control is highly desired in the breeding, breeding and housing of agricultural and domestic animals. Unfortunately, Trimite is chemically unstable in the presence of solvents with reactive hydroxyl groups such as alcohols, glycols, water, and the like. This property has limited the deve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N37/52A01N37/18A01P7/02A01N43/08
CPCY02A50/30
Inventor 肖芭恩·沙希·萨布尼斯雅各布·A·朱潘罗伯特·布鲁斯·奥尔布赖特
Owner WYETH LLC
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