Supercharge Your Innovation With Domain-Expert AI Agents!

Bilayer tablet comprising telmisartan and amlodipine

A technology of telmisartan and amlodipine, which is applied in the direction of medical preparations containing active ingredients, pill delivery, metabolic diseases, etc., can solve problems such as incompatibility and stability, and achieve the goal of promoting dissolution and solving stability problems Effect

Inactive Publication Date: 2007-10-10
BOEHRINGER INGELHEIM INT GMBH
View PDF5 Cites 40 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The tablet structure also solves the stability problem caused by the incompatibility of the basic components of amlodipine and telmisartan

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Bilayer tablet comprising telmisartan and amlodipine
  • Bilayer tablet comprising telmisartan and amlodipine

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment

[0104] Component

[0105] * Volatile components do not remain in the final product

[0106] Component

[0107] * Volatile components do not remain in the final product

[0108] Component

[0109] * Volatile components do not remain in the final product

[0110] Component

[0111] * Volatile components do not remain in the final product

[0112] Component

[0113] * Volatile components do not remain in the final product

[0114] Component

[0115] * Volatile components do not remain in the final product

[0116] Component

[0117] * Volatile components do not remain in the final product

[0118] Component

[0119] * Volatile components do not remain in the final product

[0120] Component

[0121] * Volatile components do not remain in the final product

[0122] Component

[0123] * Volatile components do not remain in the final product

[0124] ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A bilayer tablet comprises a first layer formulated for instant release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix and a second layer formulated for instant release of the calcium channel blocker amlodipine from a disintegrating or eroding tablet matrix.

Description

[0001] The present invention relates to a first layer comprising the angiotensin II receptor antagonist telmisartan in a dissolving tablet matrix and a second layer of the calcium ion channel blocker amlodipine in a disintegrating or eroding tablet matrix. Layers of medicine tablets. Background of the invention [0002] As disclosed in EP-A-502314, Telmisartan is an angiotensin II receptor antagonist developed for the treatment of hypertension and other medical indications. Its chemical name is 4'-[2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-ylmethyl]- Biphenyl-2-carboxylic acid; [0003] [0004] Telmisartan is manufactured and supplied in the free acid form. It is characterized by very poor solubility in aqueous systems of the gastrointestinal tract in the physiological pH range between pH 1 and pH 7. As disclosed in WO 00 / 43370, crystalline telmisartan exists in two polymorphic forms with different melting points. Under the influence of heat and ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/20A61K31/4184A61K31/4422A61P9/00A61P9/04A61P9/08A61P9/10A61P9/12A61P3/10A61P25/28
CPCA61K31/455A61K9/2009A61K9/2013A61K9/2018A61K9/2054A61K9/2059A61K9/2077A61K9/209A61K31/4184A61K31/4422A61P13/12A61P25/00A61P25/28A61P3/00A61P3/10A61P3/04A61P3/06A61P3/08A61P43/00A61P9/00A61P9/04A61P9/08A61P9/10A61P9/12A61K2300/00
Inventor 沃尔弗拉姆·艾森赖克
Owner BOEHRINGER INGELHEIM INT GMBH
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com