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Application of theasaponin in preparing externally applied spermicidal contraceptive

A tea saponin and drug technology, applied in the field of external spermicidal contraception, can solve the problems of delaying the disease, increasing the height, endangering the life of patients and the like

Inactive Publication Date: 2007-12-19
郭凯
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The contraceptive failure rate caused by the use of condoms accounts for the highest proportion in the above survey, and its contraceptive reliability needs to be improved
Women with intrauterine devices (IUD) still have pregnancy with a ring, and the incidence rate is still relatively high. The possibility of ectopic pregnancy or even ectopic pregnancy rupture and massive bleeding is significantly higher than that of women without IUD contraception. The onset is hidden and often leads to misdiagnosis , Missed diagnosis, delayed treatment, endangering patient's life
After years of continuous improvement, oral contraceptives have high contraceptive reliability and reduced side effects, but they are still not suitable for some people, often causing endocrine disorders, menstrual disorders, or accompanied by adverse reactions such as dizziness and nausea. Drugs have no obvious preventive and therapeutic effects on reproductive tract infections

Method used

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  • Application of theasaponin in preparing externally applied spermicidal contraceptive

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Embodiment Construction

[0019] The present invention will be further described below in conjunction with embodiment.

[0020] The medicine of the invention is mainly composed of tea saponin, and may also contain one or more kinds of traditional Chinese medicines such as Sophora flavescens, Fructus Cnidii and Curcuma.

[0021] The preparation method of medicine of the present invention, can refer to following method:

[0022] (1) After the tea saponin is separated and purified, an appropriate amount of matrix is ​​added to process it into a suppository.

[0023] (2) After the tea saponin is separated and purified, an appropriate amount of matrix is ​​added and processed into effervescent tablets.

[0024] (3) After the tea saponin is separated and purified, an appropriate amount of substrate is added to process it into a gel.

[0025] (4) After the tea saponin is separated and purified, an appropriate amount of substrate is added to process a film-forming agent.

[0026] (5) After the tea saponin i...

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Abstract

The present invention discloses new use of theasaponin, and uses theasaponin in external spermicidal contraceptive. Theasaponin in relatively concentration can kill sperm fast, and has certain antibiotic effect, low cost and high safety. The extracorporeal spermicidal experiment and rabbit contraceptive experiment show that theasaponin has lowest spermicidal concentration of 2.27 g / l for 20s and 1.19 g / l for 3 min, and rabbit contraceptive rate of 100 % when the amount is 100 mg and 50 mg.

Description

technical field [0001] The invention relates to the discovery of a new application of tea saponin, specifically, the tea saponin is used as the main component in the field of external spermicide and contraception. Background technique [0002] There are many types of contraceptive methods, and spermicide is one of the oldest and easiest vaginal contraceptives. In 1856, after Kolliker first discovered that an organic drug had a spermicidal effect, researchers screened a large number of spermicidal drugs. By 1964, there were 23 kinds officially approved by the International Planned Parenthood Federation. But in the mid-to-late 1960s, due to the advent and popularization of steroid hormone oral contraceptives and intrauterine devices, spermicide lost its important position in contraceptive measures. In recent years, with the in-depth research and wide application of oral contraceptives and intrauterine devices, their side effects have become more prominent than before. Looki...

Claims

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Application Information

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IPC IPC(8): A61K31/56A61K9/06A61K9/02A61K9/20A61K9/46A61K9/00A61P15/16
Inventor 郭凯
Owner 郭凯
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