Slow-soluble external contraceptive membrane

Abstract

The invention discloses a slow-soluble external contraceptive membrane. The contraceptive membrane is prepared from the raw materials such as 0.05 to 1.5 parts of nonoxinol-9, 0.3 to 2 parts of super carboxymethyl starch sodium, 0.3 to 3 parts of hydroxypropyl methyl cellulose, 0.1 to 0.3 part of polyacrylic resin film agent, 1 to 3 parts of polyethylene glycol, 2 to 10 parts of lubricating agentand the like. The contraceptive membrane prepared by using the material composition has slow solubility and high medicament dissolution, and has effects of absorbing seminal fluid and killing sperms.After the contraceptive membrane prepared from the materials is put into the vagina, sexual intercourse can be performed immediately, and waiting is not needed. The stiff and smooth membrane shape iskept for 3 hours when the contraceptive membrane is not contacted with the seminal fluid, and sperm killing medicaments are slowly released, so that loss of the sperm killing medicaments in short time can be avoided; and the release of the sperm killing medicaments is accelerated when the contraceptive membrane is contacted with the seminal fluid, and the performance ensures high efficiency of the sperm killing medicaments and can improve the contraceptive effect. The membrane material has good compatibility with vaginal mucosa, has irritability resistance, flexibility and comfort, and can eliminate the stimulation effect of the nonoxinol-9 on the skin mucosa.

Description

technical field [0001] The invention relates to a contraceptive film material composition, in particular to a slow-dissolving external contraceptive film. Background technique [0002] The nonoxynol film currently used in the market is a dry paper-like film that melts within 3 minutes when it meets water. In the process of pushing it into the vagina with your fingers, the film can absorb vaginal secretions and stick to your fingers, making the medicine Concentration decreased. After decades of clinical use, it has been found that its contraceptive efficiency is lower than other contraceptive methods, and it also has the disadvantage of being inconvenient to use, that is, it takes 5-10 minutes to have sexual intercourse after being inserted into the vagina. Well, it will also affect the contraceptive effect. Another disadvantage is the presence of local irritation. After use, most people will experience adverse reactions such as local burning sensation, increased secretions...

AI Technical Summary

Problems solved by technology

After decades of clinical use, it has been found that its contraceptive efficiency is lower than other contraceptive methods, and it also has the disadvantage of being inconvenient to use, that is, it takes 5-10 minutes to have sexual intercourse after being inserted into the vagina. Well, it will also affect the contraceptive effect

Another disadvantage is the presence of local irritation. After use, most people will experience adverse reactions such as local burning sensation, increased secretions, genital itching, and urinary tract infection.

Although many scientific researchers have improved the formulations of contraceptives for external use in various aspects, they still have not overcome the above shortcomings, which seriously affects the use of nonoxynol membranes.

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