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Method of preparing the tablet for hepatitis disease

A technology for liver disease and traditional Chinese medicine tablets, which is applied in the direction of antiviral agents, medical preparations containing active ingredients, and pill delivery, etc. Softening and other problems, to achieve the effect of stable and controllable quality, reasonable and feasible pilot test, and reasonable ratio

Active Publication Date: 2011-03-16
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the drug was launched on the market, it has been welcomed by doctors and patients because of its definite curative effect and no obvious side effects. However, because the preparation is a capsule, it is inconvenient to swallow. Softened by moisture absorption or hardened and brittle by weathering, resulting in poor stability of the preparation
And capsules are less effective in masking the bad smell and taste of the preparation, and this product contains animal medicine pig gall powder, so it also reduces the compliance of patients when taking it.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: according to the number of shares of each raw material in Wulinggan Complex Tablets, get the following prescription raw materials:

[0044] Schisandra 1000g, Ganoderma lucidum 400g, Salvia miltiorrhiza 300g, pig gall powder 20g, mung bean 150g

[0045] The above five flavors, mung beans are crushed into fine powder, sieved (80 mesh), and set aside; Schisandra is crushed into coarse powder, and 4 times the amount of 75% ethanol is added each time for reflux extraction three times, the first time is 3 hours, the second time, and the third time 2 hours each, filter, combine the filtrates, recover ethanol under reduced pressure, and set aside; crush Ganoderma lucidum into coarse powder, add 75% ethanol and soak at 50°C for 24 hours, filter, recover ethanol under reduced pressure, set aside; mix medicinal dregs with Salvia miltiorrhiza, Add 8 times the amount of water to decoct three times, each time for 2 hours, filter, combine the filtrate, concentrate to a c...

Embodiment 2

[0046] Embodiment 2: according to the number of shares of each raw material in Wulinggan Complex Tablets, get the following prescription raw materials:

[0047] Schisandra 1000g, Ganoderma lucidum 400g, Salvia miltiorrhiza 300g, pig gall powder 20g, mung bean 150g

[0048] The above five flavors, mung beans are crushed into fine powder, sieved (80 mesh), and set aside; Schisandra is crushed into coarse powder, and 5 times the amount of 75% ethanol is added each time for reflux extraction three times, the first time is 3 hours, the second time, and the third time 2 hours each, filter, combine the filtrates, recover ethanol under reduced pressure, and set aside; crush Ganoderma lucidum into coarse powder, add 75% ethanol and soak at 50°C for 24 hours, filter, recover ethanol under reduced pressure, set aside; mix medicinal dregs with Salvia miltiorrhiza, Add 10 times the amount of water to decoct three times, each time for 2 hours, filter, combine the filtrate, concentrate to a ...

Embodiment 3

[0049] Embodiment 3: according to the number of shares of each raw material in Wulinggan Complex Tablets, get the following prescription raw materials:

[0050] Schisandra 1000g, Ganoderma lucidum 400g, Salvia miltiorrhiza 300g, pig gall powder 20g, mung bean 150g

[0051] The above five flavors, mung beans are crushed into fine powder, sieved (80 mesh), and set aside; Schisandra is crushed into coarse powder, and 3 times the amount of 75% ethanol is added each time for reflux extraction three times, the first time is 3 hours, the second time, and the third time 2 hours each, filter, combine the filtrates, recover ethanol under reduced pressure, and set aside; crush Ganoderma lucidum into coarse powder, add 75% ethanol and soak at 50°C for 24 hours, filter, recover ethanol under reduced pressure, set aside; mix medicinal dregs with Salvia miltiorrhiza, Add 6 times the amount of water to decoct three times, each time for 2 hours, filter, combine the filtrate, concentrate to a c...

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PUM

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Abstract

The invention relates to a five-element compound medicinal tablet for treating hepatic diseases and process for preparation, wherein the raw materials include schisandra fruit, ganoderma lucidum, root of red rooted saliva, pig gall powder and mung beans. The preparation has the functions of promoting body fluid secretion, soothing liver, clearing heat and detoxicating.

Description

technical field [0001] The invention relates to a Wulinggan compound tablet for treating liver diseases and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. technical background [0002] Chronic viral hepatitis, mostly B or non-A non-B acute hepatitis protracted, migration. The general course of the disease is more than 6 months, mainly including chronic persistent hepatitis and chronic active hepatitis. According to the epidemiological survey report, there are 120 million people in my country who carry hepatitis B virus, and there are 30 million chronic hepatitis patients. 38 million people are infected with HCV, 50% of whom still carry the virus. [0003] Wulingganfu Capsules have the effects of nourishing yin and promoting body fluid, soothing the liver and relieving stagnation, clearing away heat and detoxifying, and are mainly used for the treatment of chronic viral hepatitis with liver and kidney deficiency and damp-hea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/57A61K9/20A61P1/16A61P31/14A61P31/20A61K35/413
Inventor 张卫华
Owner BEIJING INCREASEPHARM CORP LTD
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