Pharmaceutical combination for improving skin oil-water balance and acne symptom and preparation thereof

A technology for improving skin and composition, applied in the preparation of the pharmaceutical composition, in the field of pharmaceutical composition that can improve skin oil-water balance and acne symptoms, and can solve the problems of large dosage, low utilization rate of medicinal materials, inconvenient carrying, etc.

Inactive Publication Date: 2008-08-06
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Based on the above patent documents, it can be seen that the dosage form is still mostly in the original dosage form, and there are problems such as large dosage and inconvenient to carry, and all of them are extracted with water, so the utilization rate of medicinal materials is low
[0004] Based on the above analysis, taking into account today's fast-paced lifestyle and young people's consumption preferences, the inventors based on the traditional "Guiling Jelly" basic prescription, and adjusted other non-main medicines of the original prescription according to the theory of traditional Chinese medicine, forming a suitable depth. The prescription that is convenient to make modern popular dosage form such as " soft capsule " of development, this prescription has not found any report about the pharmaceutical composition of the present invention so far

Method used

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  • Pharmaceutical combination for improving skin oil-water balance and acne symptom and preparation thereof
  • Pharmaceutical combination for improving skin oil-water balance and acne symptom and preparation thereof
  • Pharmaceutical combination for improving skin oil-water balance and acne symptom and preparation thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0030] Embodiment 1 (preparation of the soft capsule of pharmaceutical composition of the present invention)

[0031] a) Take by weighing 750g turtle shell, 188g Smilax cocos, 188g honeysuckle, 188g habitat, 19g dandelion;

[0032] b) Crush the tortoise shell, add 3 times the amount of water and decoct 3 times, 2 hours each time. The three decoctions were combined, filtered to obtain filtrate 1, concentrated and dried at about 80°C to obtain dry extract 1;

[0033]c) Smilax smilax, honeysuckle, dandelion plus 60% ethanol for reflux extraction, recover ethanol from the extract, and dry at 75°C to obtain dry extract 2;

[0034] d) Add 10 times the amount of water to the fresh ground and decoct twice, each time for 1 hour, combine the decoction twice, filter to obtain the filtrate 2, concentrate it into an extract with a specific gravity of 1.35, add 95% ethanol for alcohol precipitation, and recover ethanol and concentrated, dried at 60°C to obtain dry extract 3.

[0035] e) ...

Embodiment 2

[0036] Embodiment 2 (preparation of the hard capsule of pharmaceutical composition of the present invention)

[0037] a) Crush 800g of tortoise shell, add 3 times the amount of water and decoct 3 times, each time for 2 hours. The three decoctions were combined, filtered to obtain filtrate 1, concentrated and dried at about 60°C to obtain dry extract 1;

[0038] b) reflux extraction of 200g Smilax smilax, 200g honeysuckle, 20g dandelion plus 60% ethanol, recover ethanol from the extract, and dry at 75°C to obtain dry extract 2;

[0039] c) Decoct 200g raw land with 10 times the amount of water for 2 times, each time for 1 hour, combine the 2 decoctions, filter to obtain filtrate 2, concentrate it into an extract with a specific gravity of 1.35, add 90% ethanol for alcohol precipitation, and recover ethanol and concentrated, and dried at 60°C to obtain dry extract 3.

[0040] d) Merge dry extract 1, dry extract 2 and dry extract 3, in the follow-up process: pulverize it into p...

Embodiment 3

[0041] Embodiment 3 (preparation of pharmaceutical composition granule of the present invention)

[0042] a) Take by weighing 800g turtle shell, 200g Smilax cocos, 200g honeysuckle, 200g habitat, 20g dandelion;

[0043] b) Crush the tortoise shell, decoct it with water, filter the decoction to obtain filtrate 1, concentrate and dry at about 70°C to obtain dry extract 1;

[0044] c) Reflux extraction of Smilax smilax, honeysuckle, and dandelion plus 10%-95% ethanol, recover ethanol from the extract, and dry at about 50°C to obtain dry extract 2;

[0045] d) Decoct raw rehmanniae with water, filter the decoction to obtain filtrate 2, concentrate it into an extract with a specific gravity of 1.35, add 90-95% ethanol for alcohol precipitation, recover ethanol and concentrate, dry at about 60°C, and prepare Get dry extract3.

[0046] e) Merge dry extract 1, dry extract 2 and dry extract 3, in the follow-up process: pulverize it into fine powder, add appropriate amount of dextrin ...

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Abstract

The invention discloses a medicine composition that can improve the skin oil-water balance and acne symptoms, which mainly adopts tortoise plastron and smilax glabra to combine and prepares any acceptable formulation in practical pharmacy. The specific dosage is 1-10 shares of tortoise plastron and 1-6shares of smilax glabra. The medicine composition of the invention has the functions of supplementing yin and clearing heat and detoxification, removing dampness-heat, sore toxicity and pimples and so on, which is used for health care and regulating the symptoms of rough skin, astriction, etc., resulted from yin deficiency and fire excess. In addition, the invention also discloses a preparation method for the medicine composition.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a pharmaceutical composition capable of improving skin oil-water balance and acne symptoms; in addition, the invention also relates to a preparation method of the pharmaceutical composition. Background technique [0002] In today's society, due to excessive competitive pressure or improper diet, many young practitioners have symptoms such as rough skin, facial acne, and constipation caused by yin deficiency and fire. Such symptoms are generally mild and do not reach the level that requires "treatment". Generally, drug treatment is not advocated, and there is no good treatment method with Western medicine. This is where the advantages of Chinese medicine being good at "conditioning" are reflected. According to the theory of traditional Chinese medicine, taking orally the compound prescription of traditional Chinese medicine with the effect of nourishing yin and regulating it...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P17/10A61K35/56A61K35/586
Inventor 张永太李国文韩向东张默存况晓田俊峰
Owner SHANGHAI UNIV OF T C M
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