Agglutination assay

An analysis method and analyte technology, applied in the field of agglutination analysis, can solve problems such as difficult electronic recording of data, loss of sensitivity, damage to efficacy, etc., and achieve the effects of improving needs, enhancing sensitivity, and simplifying manufacturing
CN101305282AInactive Publication Date: 2008-11-12PLATFORM DIAGNOSTICS LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
PLATFORM DIAGNOSTICS LTD
Publication Date
2008-11-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to agglutination assays and related kits, reagents and devices. In particular methods of assaying small analytes having few epitopes are disclosed, by means of using hub moieties to which multiple analytes may be bound by a first epitope, together with a further moiety capable of binding a second analyte epitope and which is also capable of binding to a detectable particle. Stable agglutinated complexes may be so formed, which may used as the basis for various assay formats.
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Description

field of invention

[0001] The present invention relates to an agglutination assay for detecting an analyte in a sample. In particular, the present invention relates to assays and assay devices based on porous supports, kits comprising means for performing such assays, and assay methods for detecting analytes in samples. Background of the invention

[0002] Immunoassays are well-established techniques for the detection and quantification of analytes in samples. They are particularly suitable for detecting and / or measuring substances in biological samples as an aid in the diagnosis and prognosis of diseases, and for predicting a patient's response to treatment. Technologies that have revolutionized diagnostic medicine, such as radioimmunoassays and enzyme immunoassays, are based on the detection of antibody-antigen interactions. A number of detection systems are available, including the use of radioactive or enzyme-labeled antigens, antibodies or complexes thereof. Many req...

Claims

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