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Cap-shaped contraceptive gel preparation

A gel preparation and cap-shaped technology, which is applied in the field of cap-shaped gel preparations, can solve problems such as side effects and easy fall-off of the cervical cap, and achieve the effect of easy acceptance and convenient use

Inactive Publication Date: 2009-09-09
大连永兴生物医药孵化器有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Condoms will bring discomfort to both parties, and the cervical cap is easy to fall off, causing the danger of conception, while oral contraceptives and spermicides will bring side effects to the body

Method used

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  • Cap-shaped contraceptive gel preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] In 1000 g of gel preparation for contraception:

[0017] (1) 580g sodium carboxymethylcellulose and 300g polyvinyl alcohol are mixed uniformly;

[0018] (2) Add 100g of glycerin, 20g of Tween-80, and 2000ml of deionized water into (1), and stir well at a temperature of 50°C to 90°C to make a gel paste-like raw material;

[0019] (3) When the temperature of the raw material drops to 45°C, it is formed through a mold;

[0020] (4) After cooling and solidifying, a cap-shaped contraceptive gel preparation is prepared.

Embodiment 2

[0022] In 1000 g of gel preparation for contraception:

[0023] (1) 500g sodium carboxymethylcellulose, 80g sodium starch glycolate, and 300g polyvinyl alcohol are mixed uniformly;

[0024] (2) Add 100g of glycerin, 20g of Tween-80, and 2000ml of deionized water into (1), and stir well at a temperature of 50°C to 90°C to make a gel paste-like raw material;

[0025] (3) When the temperature of the raw material drops to 45°C, it is formed through a mold;

[0026] (4) After cooling and solidifying, a cap-shaped contraceptive gel preparation is prepared.

Embodiment 3

[0028] In 1000 g of gel preparation for contraception:

[0029] (1) 500g sodium carboxymethylcellulose, 80g chitosan, and 300g polyvinyl alcohol are mixed uniformly;

[0030] (2) Add 100g of glycerin, 20g of Tween-80, and 2000ml of deionized water into (1), and stir well at a temperature of 50°C to 90°C to make a gel paste-like raw material;

[0031] (3) When the temperature of the raw material drops to 45°C, it is formed through a mold;

[0032] (4) After cooling and solidifying, a cap-shaped contraceptive gel preparation is prepared.

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PUM

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Abstract

The invention relates to a cap-shaped contraceptive gel preparation, which is compounded by carboxymethylcellulose sodium and other gels. The cap-shaped contraceptive gel preparation has the advantages that: 1, the preparation can rapidly absorb water (tissue fluid) in cervical ostium, is expanded and dissolved, and generates biological adhesion which is firmly adhered on the cervical ostium and covers the cervical ostium to achieve the aim of contraception; 2, after the gel entering cervix is dissolved, a protective layer with high gel viscosity is formed in the cervical ostium to deactivate sperm so as to achieve the effect of contraception; 3, the preparation can be biodegraded in a human body and has no residue and no toxic and side effects; and 4, the preparation is convenient to use and easy to be accepted by a user.

Description

technical field [0001] The invention relates to a contraceptive cap-shaped gel preparation composed of carboxymethylcellulose sodium and other gels. Background technique [0002] At present, the methods of contraception basically include: condoms, cervical caps, oral contraceptives, spermicides, etc. Condoms will bring discomfort to both parties, and the cervical cap is easy to fall off, causing the danger of conception, while oral contraceptives and spermicides will bring side effects to the body. Contents of the invention [0003] In order to overcome the disadvantages of condoms, cervical caps, oral contraceptives, and spermicides causing side effects, the invention provides a gel preparation compounded by sodium carboxymethylcellulose and other gels. [0004] The sodium carboxymethylcellulose accounts for 0.1% to 60% by weight of the suppository. [0005] The gel is: carbomer, methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/04A61F6/00
Inventor 冯伯智滕锡山
Owner 大连永兴生物医药孵化器有限公司