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Compound medicament for treating children cough and preparation method thereof

A compound and children's technology, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of side effects, small side effects, and unsatisfactory effects of western medicines, and achieve precise compatibility, small prescriptions, and definite effects. Effect

Active Publication Date: 2009-12-23
JIANMIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved in the present invention is to overcome the unsatisfactory effect of existing western medicines for treating cough in children and the defects of certain side effects, and provide a compound medicine for treating cough in children and a preparation method thereof, which has remarkable curative effect in treating cough in children, High purity, less side effects

Method used

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  • Compound medicament for treating children cough and preparation method thereof
  • Compound medicament for treating children cough and preparation method thereof
  • Compound medicament for treating children cough and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] a: Extraction of volatile oil: 80 grams of mint, 80 grams of nepeta panicles, 80 grams of fried Fructus Aurantii, 80 grams of Peucedanum, add 1920mL of water, soak for 1 hour, reflux to extract volatile oil for 4 hours, and obtain about 1.6mL of volatile oil for later use, after distillation The aqueous solution was collected in another device.

[0023] b: Extraction of burdock fruit and other preparations: the dregs obtained in step a, 130 grams of burdock fruit, 130 grams of mulberry leaves, 120 grams of Radix Isatidis, 120 grams of aster, 80 grams of licorice, five herbs, 9000mL, 7200mL, 7200mL of water, decocted 3 times , 2 hours, 1.5 hours, 1.5 hours each time, combine the decoction, filter, combine the filtrate with the aqueous solution of step a, concentrate to about 964g of clear paste with a relative density of 1.10-1.12 (60-75°C), let cool to room temperature , slowly add ethanol while stirring, so that the alcohol content reaches 60%, let it stand for 12 hour...

Embodiment 2

[0027] a: Extraction of volatile oil: 40 grams of mint, 40 grams of nepeta panicles, 40 grams of fried Fructus Aurantii, 40 grams of Peucedanum, add 960 mL of water, soak for 1 hour, reflux to extract volatile oil for 4 hours, and obtain about 0.8 mL of volatile oil for later use, after distillation The aqueous solution was collected in another device.

[0028]b: Extraction of burdock fruit and other preparations: the medicinal residue obtained in step a, 70 grams of burdock fruit, 70 grams of mulberry leaves, 60 grams of Radix Isatidis, 40 grams of aster, 20 grams of licorice, five herbs, 4200mL, 3336mL, 3360mL of water, decocting 3 times , each time for 2 hours, 1.5 hours, 1.5 hours, combine the decoction, filter, combine the filtrate with the aqueous solution of step a, concentrate to about 471g of clear paste with a relative density of 1.10-1.12 (60-75°C), let cool to room temperature , slowly add ethanol while stirring, so that the alcohol content reaches 60%, let it stan...

Embodiment 3

[0032] a: Extraction of volatile oil: 66.7 grams of mint, 66.7 grams of nepeta panicles, 66.7 grams of fried Fructus Aurantii, 66.7 grams of Peucedanum, add 1920mL of water, soak for 1 hour, reflux to extract volatile oil for 4 hours, and obtain about 1.3mL of volatile oil for later use, after distillation The aqueous solution was collected in another device.

[0033] b: Extraction of burdock fruit and other preparations: the dregs obtained in step a, 100 grams of burdock fruit, 100 grams of mulberry leaves, 83.3 grams of Radix isatidis, 83.3 grams of aster, 50 grams of licorice, five herbs, 6834 mL, 5467 mL, 5467 mL of water, decocted 3 times , 2 hours, 1.5 hours, 1.5 hours each time, combine the decoction, filter, combine the filtrate with the aqueous solution of step a, concentrate to about 766g of clear paste with a relative density of 1.10-1.12 (60-75°C), let cool to room temperature , slowly add ethanol while stirring, so that the alcohol content reaches 60%, let it stan...

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Abstract

The invention discloses a compound medicament for treating children cough and a preparation method thereof. The compound medicament comprises the following raw materials in portion by weight for preparing active components: 70 to 130 portions of fructus arctii, 70 to 130 portions of mulberry leaf, 15 to 45 portions of bulbus fritillariae cirrhosae, 40 to 80 portions of mint, 60 to 120 portions of radix isatidis, 40 to 80 portions of schizonepeta spike, 40 to 80 portions of fried fructus aurantii, 40 to 80 portions of radix peucedani, 40 to 120 portions of aster, and 20 to 80 portions of licorice. The preparation method comprises the following steps: a, extracting the mint, the schizonepeta spike, the fried fructus aurantii and radix peucedani volatile oil; b, extracting and preparing the fructus arctii and the like; c, extracting and preparing the bulbus fritillariae cirrhosae; and d, preparing a finished medicament. The compound medicament has significant curative effect, high purity and small side effects for treating the children cough. The preparation method has the advantages of high extraction yield, high purity, simple operation, and suitability for industrialized production.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a compound medicine for treating cough in children and a preparation method thereof. Background technique [0002] Pediatric (0-14 years old) exogenous cough, mainly refers to Western medicine called acute tracheo-bronchitis, is a common respiratory disease in children, accounting for about 70-80% of pediatric outpatient visits. Western medicine believes that this disease is an acute inflammatory reaction of the trachea-bronchial mucosa caused by viral bacterial infection, physical and chemical stimulation or allergic reaction, with cough and expectoration as the main symptoms; After exertion, young children have a higher incidence than adults [1]. The results of the fifth national census show that the population aged 0-14 accounts for 22.89% of the total population in my country, with a total of 296.5 million people. According to statistics, 1 in every 10 ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K9/10A61P11/14
Inventor 朱鸿龙
Owner JIANMIN PHARMA GRP CO LTD
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