Method for distinguishing coating quality of medicine preparation

A pharmaceutical preparation and coating technology, applied in the identification of the coating quality of pharmaceutical preparations and the identification of coating quality, can solve the problems of labor and time-consuming, increasing errors, inability to comprehensively evaluate the coating quality, etc., and achieves good prediction ability, The effect of reducing interference, ensuring effectiveness and rationality
CN101713731AActive Publication Date: 2010-05-26河北鑫民和质检技术服务有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
河北鑫民和质检技术服务有限公司
Publication Date
2010-05-26

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Abstract

The invention belongs to the field of medicine preparations, which in particular relates to a method for distinguishing the coating quality. More concretely, the invention relates to a method for distinguishing the coating quality of a medicine preparation. In the method provided by the invention, a qualitative distinguishing model of the coating quality is quickly constructed by combining the methods of a near-infrared spectrum method, an interval principal component analysis method, a support vector machine method and the like, the comprehensive evaluation of the coating quality of the medicine preparation is realized, and the distinguishing accuracy basically reaches the requirement of industrial production. Relative to a traditional method or experiential judgment, the distinguishing method provided by the invention can quickly, nondestructively, reliably and accurately distinguish the coating quality of the medicine preparation in a coating process in an on-line way.
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Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a method for identifying coating quality. More specifically, the present invention relates to a method for identifying the coating quality of pharmaceutical preparations. Background technique

[0002] Tablets made by direct compression, if the properties of the drug are unstable, have bad smell, irritate the stomach, or are easily damaged by gastric juice, etc., it is usually necessary to wrap a layer of excipients on the surface to isolate the drug in the tablet from the outside world , so as to further ensure the quality of the tablet. The quality of the coating layer directly affects the coating effect. If the coating layer is too thin, it cannot meet the requirements of protecting the tablet core, while if it is too thick, it will not be conducive to the disintegration of the coated tablet, and at the same time lead to an increase in cost.

[0003] In ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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