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Traditional Chinese medicine composite for protecting livers and preventing liver injury and preparation method thereof

A composition and technology for liver damage, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of lack of reports, liver damage, etc., and achieve the effect of reducing liver damage and reducing liver damage

Inactive Publication Date: 2010-10-27
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Whether the compatibility of traditional Chinese medicine can not only exert the clinical curative effect of gardenia jasminoides, but also avoid its toxic side effects of liver damage, the existing literature is also lack of reports

Method used

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  • Traditional Chinese medicine composite for protecting livers and preventing liver injury and preparation method thereof
  • Traditional Chinese medicine composite for protecting livers and preventing liver injury and preparation method thereof
  • Traditional Chinese medicine composite for protecting livers and preventing liver injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Weigh the raw materials: Sunburn Astragalus 20g, Atractylodes macrocephala 10g, Poria cocos 10g, licorice 10g, Schisandra 10g, decoct twice with water, and concentrate to a concentration equivalent to crude drug 0.55g ml -1 .

Embodiment 2

[0035] Weigh raw materials: Radix Astragali 25g, Atractylodes macrocephala 12.5g, Poria cocos 12.5g, licorice 12.5g, Schisandra 12.5g, decoct twice with water, and concentrate to a concentration equivalent to crude drug 0.65g ml -1 .

Embodiment 3

[0037] Weigh raw materials: Radix Astragali 30g, Atractylodes macrocephala 15g, Poria cocos 15g, licorice 15g, Schisandra chinensis 15g, decoct twice with water, and concentrate to a concentration equivalent to crude drug 0.75g ml -1 .

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Abstract

The invention discloses a traditional Chinese medicine composite for protecting livers and preventing liver injury and a preparation method and application thereof. The composite comprises the following bulk drugs in parts by weight: 20-30 parts of astraglus base, 10-15 parts of bighead atractylodes rhizome, 10-15 parts of tuckahoe, 10-15 parts of liquorice and 10-15 parts of Schisandra chinensis. The preparation method comprises the following steps of: adding water to the bulk drugs in percentage by weight and decocting, and concentrating until the concentration is equivalent to 0.55-0.75g.ml-1 which is the concentration of crude drugs. Proved by animal experiment pathological study, the spleen-tonifying and liver-protecting prescription of the invention does not have hepatotoxicity per se and has a certain function of preventing mice acute liver injury caused by CCl4. The prescription not only can relieve the liver injury of jasmine on normal mice but also can assist routine dosage of jasmine to prevent the mice acute liver injury caused by CCl4. The invention is safe and effective and has low price and is suitable for patients with chemical and medicament liver injury.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for protecting the liver and preventing liver damage, its preparation method and application. Background technique [0002] Traditional Chinese medicine has made great contributions to the prosperity of the Chinese nation. In recent years, traditional Chinese medicine, as a "green" and "natural" medicine, has attracted more and more attention from the international medical community. With the frequent international exchanges, traditional Chinese medicine has gradually occupied a place in the overseas health care products market and treatment field. However, "green" and "natural" are not "safe". With the wide application of traditional Chinese medicine, the toxic and side effects of some traditional Chinese medicine are also increasingly concerned. [0003] Guan Mutong in Longdan Xiegan Decoction, which has recei...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/57A61K36/744A61P1/16
Inventor 徐列明林庆勋
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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