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Compound injection for repelling internal and external parasites of animal bodies and preparation method thereof

A technology for injections and parasites, which is applied in the field of compound injections and preparations for expelling internal and external parasites in animals, and can solve the problems of arthropod parasites being ineffective

Inactive Publication Date: 2011-03-23
TIANJIN RINGPU BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0027] Macrolide drugs such as ivermectin focus on nematodes in animals and arthropod parasites parasitic in the skin, but are ineffective against flukes and tapeworms; praziquantel is effective against nematodes, flukes, and tapeworms in animals, but is effective against Arthropod parasites that live in the skin are not effective

Method used

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  • Compound injection for repelling internal and external parasites of animal bodies and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] (1) Prescription (1000ml)

[0036] Ivermectin 6g, Praziquantel 30g, Benzyl Alcohol 7.5ml, Propylene Glycol 150ml

[0037] (2) Process

[0038] Weigh 6g of raw materials ivermectin and 30g of praziquantel, heat and dissolve with propylene glycol, add 7.5ml of benzyl alcohol, add to the dispenser, slowly dilute to 1000ml with an appropriate amount of refined soybean oil, mix the above solutions evenly, coarsely filter, and refine Filtration, filling and sealing, sterilization, light inspection, packaging and storage.

Embodiment 2

[0040] (1) Prescription (1000ml)

[0041] Ivermectin 10g, Praziquantel 50g, Benzyl Alcohol 7.5ml, Propylene Glycol 150ml

[0042] (2) Process

[0043] Weigh 10g of raw materials ivermectin and 50g of praziquantel, heat and dissolve with propylene glycol, add 7.5ml of benzyl alcohol, add to the dispenser, slowly dilute to 1000ml with an appropriate amount of refined soybean oil, mix the above solutions evenly, coarsely filter, and finely Filtration, filling and sealing, sterilization, light inspection, packaging and storage.

Embodiment 3

[0045] (1) Prescription (1000ml)

[0046] Ivermectin 12g, Praziquantel 60g, Benzyl Alcohol 7.5ml, Propylene Glycol 150ml

[0047] (2) Process

[0048] Weigh 10g of raw materials ivermectin and 50g of praziquantel, heat and dissolve with propylene glycol, add 7.5ml of benzyl alcohol, add to the dispenser, slowly dilute to 1000ml with an appropriate amount of refined soybean oil, mix the above solutions evenly, coarsely filter, and finely Filtration, filling and sealing, sterilization, light inspection, packaging and storage.

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Abstract

The invention relates to a compound injection for repelling internal and external parasites of animal bodies and a preparation method thereof. The compound injection mainly consists of ivermectin and praziquantel. Ivermectin is a 16-membered macrolide specific medicine for preventing and treating the internal and external parasites of animal bodies and can specifically prevent and treat cardio-filaria and efficiently prevent and treat the internal parasites such as hookworm, roundworm, whipworm, bellyworm and the like and the external parasites such as Demodex folliculorum, acariasis, louse, flea and the like. Praziquantel is efficient to wireworm, trematode and cestode in the animal bodies. The worm-repelling spectrums of ivermectin and praziquantel are mutual complementary and the combination of the two medicines expands the worm-repelling spectrums and improves the worm-repelling effect at one time. The invention further provides a preparation method of the compound injection. The compound injection is used for hypodermic and has long drug-effect lasting time.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, in particular to a compound injection for expelling internal and external parasites of animals and a preparation method thereof. Background technique [0002] Anthelmintic drugs have a long history of development. As far back as 2,000 years ago, my country’s first herbal book "Shen Nong’s Materia Medica" listed more than 30 kinds of anthelmintic drugs. The earliest record of repelling (killing) insecticides. Anthelmintics such as turnip, dogwood, pomegranate root, spike, betel nut, pumpkin seeds, and torreya seeds are still used today. [0003] In the 1730s, the Spaniards discovered in Peru that the bark of the cinchona tree could treat malaria, which opened a window for the development of antiparasitic drugs into modern pharmacology. In 1820, quinine, the main alkaloid of Cinchona bark, was isolated. In the past two centuries, quinine has played an important role in the treatment an...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K31/4985A61K9/08A61P33/00A61P33/14
Inventor 霍俊凤
Owner TIANJIN RINGPU BIO TECH
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