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Traditional Chinese medicinal composition for treating headache, preparation method thereof and detection method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating headaches and its preparation method and detection, can solve the problems of large side effects, high price, unsatisfactory curative effect, etc.

Active Publication Date: 2011-04-27
庞来祥
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many medicines for the treatment of migraine, which play a certain role in the prevention and treatment of this disease, but most of them are mainly western medicines, most of which are expensive, have large side effects, and the curative effect is not satisfactory.

Method used

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  • Traditional Chinese medicinal composition for treating headache, preparation method thereof and detection method thereof
  • Traditional Chinese medicinal composition for treating headache, preparation method thereof and detection method thereof
  • Traditional Chinese medicinal composition for treating headache, preparation method thereof and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0122] Example 1: Uncaria 720g, Rhizoma Chuanxiong 480g, Scorpion 120g, Angelica dahurica 216g, Achyranthes bidentata 240g, Radix Paeoniae Alba 240g, Radix Glycyrrhizae 72g; Rhizoma Chuanxiong and Angelica dahurica add 8 times the amount of water to distill for 6h, collect volatile oil, and the residual liquid is for later use; Multiple times the amount of β-cyclodextrin was clathrated at 30°C for 1 hour to make an inclusion compound, and dried under reduced pressure; Uncaria and Scorpion were extracted with 6 times the amount of 50% ethanol for 3 times, each time for 30 minutes, and the extracts were combined to recover ethanol Concentrate to a relative density of 1.25 at 60°C until there is no alcohol smell, and set aside; add 10, 8, and 8 times the amount of water to extract 3 times for white peony root, achyranthes bidentata, and licorice, respectively. The first extraction is 1.5 hours, and the second and third extractions are each 1h, combine the extract and the residual ...

Embodiment 2

[0123] Example 2: Uncaria 360g, Rhizoma Chuanxiong 360g, Scorpio 60g, Angelica dahurica 162g, Achyranthes bidentata 120g, Radix Paeoniae Alba 180g, Radix Glycyrrhizae 36g; Rhizoma Chuanxiong and Angelica dahurica were distilled with 8 times the amount of water for 8 hours, collected volatile oil, and the residual liquid was for subsequent use; Double the amount of β-cyclodextrin at 40°C for 0.5 hours to make an inclusion complex, and dry it under reduced pressure; add 4 times the amount of 70% ethanol for Uncaria and Scorpion to extract twice, each time for 40 minutes, combine the extracts, and recover ethanol Concentrate to a relative density of 1.20 at 60°C until there is no alcohol smell, and set aside; add 12 and 10 times the amount of water to extract radix paeoniae Alba, Achyranthes bidentata, and licorice, respectively, for 2 times, the first extraction is 2 hours, the second extraction is 1.5 hours, and combined extraction liquid and the residual liquid after oil extrac...

Embodiment 3

[0124] Example 3: Uncaria 540g, Rhizoma Chuanxiong 240g, Scorpion 90g, Angelica dahurica 108g, Achyranthes bidentata 180g, Radix Paeoniae Alba 120g, Radix Glycyrrhizae 54g; Rhizoma Chuanxiong and Angelica dahurica were distilled with 12 times the amount of water for 4 hours, volatile oil was collected, and the residual liquid was set aside; Add 8 times the amount of 40% ethanol to the scorpion and extract 4 times, each time for 20 minutes, combine the extracts, recover the ethanol until it has no alcohol smell, concentrate at 60°C to a relative density of 1.30, and set aside; 8, 8, and 6 times the amount of water extraction for 4 times, the first extraction for 1.5 hours, the second and third extractions for 1 hour, and the fourth extraction for 0.5 hours. Combine the extract and the residual liquid after oil extraction, filter, and shrink to the material The liquid ratio is 1:3, add 1.0 times of 1% chitosan flocculation liquid, let it stand for 30 hours, filter, concentrate th...

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Abstract

The invention relates to a traditional Chinese medicinal composition for treating headache, a preparation method thereof and a detection method thereof. The traditional Chinese medicinal composition consists of uncaria, ligusticum wallichii, scorpion, angelica, bidentate achyranthes, white paeony root and liquoric root. The formulation may be pills, granules, hard capsules, soft capsules, tablets, drop pills or oral liquid and the like. The preparation has the characteristics of exact curing effect, desirable clinical symptom relieving effect, fewer side effects and low price. The detection method of the granules comprises lamina identification of uncaria, ligusticum wallichii, scorpion, angelica root and bidentate achyranthes and the content assay of the white paeony root.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, a preparation method and a detection method thereof, in particular to a traditional Chinese medicine composition for treating headache, a preparation method and a detection method thereof. Background technique [0002] Migraine is an intermittent, recurring, neurological disorder characterized by headaches on one side. Headache is unbearable during outbreak, and even then feels sick, vomits, and brings great misery to patient, causes work efficiency to reduce, and quality of life declines. Patients with migraine have a higher chance of developing heart disease and ischemic stroke than healthy people, and can also cause major depression and phobia. At present, there are many medicines for the treatment of migraine, which have played a certain role in preventing and treating the disease, but most of them are mainly western medicines, most of which are expensive, have great side effects...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61K9/16A61P25/04A61K35/64A61K35/646
Inventor 庞来祥
Owner 庞来祥
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