90results about How to "Shortened sleep latency" patented technology

A smart pillow unit and processes for providing active noise cancellation and biofeedback.

Described herein are tetherless, forehead-mounted temperature regulation apparatuses configured to enhance sleep.

Apparatuses and methods to enhance sleep, reduce sleep onset latency, extend sleep duration and / or increasing the duration of deeper sleep stages relative to stage 1 sleep. In general, these apparatuses and methods apply and maintain one or more target “warm” temperatures to a subject's forehead for a time period. The target temperature may be between 25° C. and 42° C. The target temperature may be a fixed amount greater than ambient temperature. The time period may be a fixed time period or a variable time period. These methods and apparatuses may limit the application of thermal energy to the subject's forehead region.

An infant calming / sleep-aid device includes a main moving platform that moves in a reciprocating manner and an actuator that drives the reciprocating movement of the main moving platform. The moving head platform is linked to the main moving platform and at least one of a motion sensing device and a sound sensing device are either at or proximate to a moving head platform that is pivotally linked to the main moving platform. A logic circuit links at least one of the motion and sound sensing devices of the infant calming / sleep aid-device to the main moving platform whereby signals detected modulate movement of the main moving platform. A sound generating device is linked to the logic circuit.

Preclinical and clinical studies have shown that the autonomic nervous system (parasympathetic and sympathetic nervous systems) show reliable changes across the sleep wake cycle. Most importantly, the parasympathetic nervous system shows increased activity during sleep consistent with its role in regulating rest. Further, patients with insomnia show reduced parasympathetic activity and / or increased sympathetic activity during sleep consistent with a neurobiological model of “hyperarousal”. Described herein are methods and apparatuses that activate the parasympathetic nervous system in response to a diving reflex; a sustained diving reflex may, surprisingly, lead to enhancing sleep. The apparatuses and methods described herein may specifically and / or selectively activate this reflex may play a therapeutic role in the modulation of sleep in insomnia patients.

A smart pillow unit and processes for providing active noise cancellation and biofeedback.

A sleep aiding apparatus for increasing the duration of deep sleep and / or reducing the sleep latency of a subject is disclosed. The sleep aiding apparatus comprises a pillow body and a device to play a sleep aiding music. Also disclosed herein are methods for aiding sleep, by providing the sleep aiding apparatus to a subject in need thereof.

The invention belongs to the technical fields of pharmaceutical preparations and healthcare foods and in particular relates to a pharmaceutical composition with an effect of improving sleep as well as a preparation method of the pharmaceutical composition and application of the pharmaceutical composition in medicines, healthcare foods and foods. The pharmaceutical composition comprises the following raw material medicines of maca, spina date seed, semen boitae, schisandra chinensis and lucid ganoderma. The medicines or healthcare foods are mainly prepared for the crowd suffering from the symptoms such as heart and liver yin-blood deficiency, lack of spirit preservation, body function reduction and poor sleep and have the effects of nourishing the blood and promoting blood circulation and calming heart and soothing nerves, so that the pharmaceutical composition has a healthcare function of improving the sleep. The preparation method is simple and economic in cost, can be used for preparing the medicines and healthcare foods for improving the sleep and has good application prospects and economic benefits.

The invention relates to a traditional Chinese medicinal composition for improving the sleep quality and a preparation of the traditional Chinese medicinal composition. The formula of the traditional Chinese medicinal composition is prepared from the following components: 30 to 50 parts of fructus citri sarcodactyli, 20 to 40 parts of lily bulb, 10 to 30 parts of semen ziziphi spinosae, 5 to 20 parts of poria cocos and 5 to 15 parts of semen nelumbinis. According to the traditional Chinese medicinal composition disclosed by the invention, the components are reasonably matched according to a traditional Chinese theoretical formula. Pharmacology experiment results show that the traditional Chinese medicinal composition has a function of improving the sleep quality; the traditional Chinese medicinal formula and an extraction method are simple; crude drugs are easily obtained; the traditional Chinese medicinal composition is low in cost and easy to produce; the quality is easy to control.

The present disclosure is a composition, a method of making the composition and method of using such composition preferably in the form of a dietary supplement that, when administered, is capable of treating insomnia and other sleep-related disorders. The unique combination of the composition is preferably administered orally. The composition is preferably comprised of at least vitamin B6, chamomile extract, passionflower extract, lemon balm extract, L-Theanine, GABA, 5-Hydroxytryptophan, and melatonin, in pre-determined amounts. The composition can further comprise a palliative agent, and can be provided in the form of a capsule, powder, liquid or tablet.

The invention provides a composition with a sedative effect and an atomization preparation thereof. The composition comprises chamomile volatile oil or lavender volatile oil, tea polyphenol and vitamin E, has sedative and tranquillizing effects, no toxic and side effects and good stability, is easy to absorb by a human body and can effectively inhibit symptoms like neurasthenia.

By combining one or more drugs selected from the group consisting of sedative antidepressants and antihistamines with (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, there is provided a prophylactic or therapeutic agent for sleep disorder that induces natural sleep, shortens sleep latency, increases deep sleep, is excellent in maintaining sleep, and exerts to attain appropriate sleep duration.

The invention provides a Chinese herbal medicinal compound preparation for improving sleep and assisting in improving memory and a preparation method of the Chinese herbal medicinal compound preparation. The invention discloses the Chinese herbal medicinal compound preparation for improving the sleepg and assisting in improving the memory. The Chinese herbal medicinal compound preparation is prepared from the following raw materials in parts by weight: 100 to 140 parts of radix ginseng, 130 to 170 parts of semen ziziphi spinosae, 40 to 80 parts of fructus schisandrae, 40 to 80 parts of sharpleaf galangal fruit, 30 to 60 parts of cortex eucommia, 40 to 80 parts of radix ophiopogonis and 40 to 70 parts of valerian root. The invention also discloses the preparation method of the Chinese herbal medicinal compound preparation for improving the sleep and assisting in improving the memory. The Chinese herbal medicinal compound preparation is proved by pharmacodynamic experiments of animals to have the efficacy of improving the sleep and assisting in improving the memory; in addition, the Chinese herbal medicinal compound preparation has the advantages of remarkable effect, small toxic or side effects, safety, reliability, simple and feasible process, convenience in taking and carrying, high bioavailability and important significance for promoting development of social economy and health.

The invention provides a chalcone compound having a function of improving sleep. The chalcone compound is used as a bulk drug for preparing various dosage types of medicines for calming and soothing the nerves or the medicines related to improvement of the sleep, and has medical application in treatment and improvement on diseases related to the sleep.

The present disclosure is a composition, a method of making the composition and method of using such composition preferably in the form of a dietary supplement that, when administered, is capable of treating insomnia and other sleep-related disorders. The unique combination of the composition is preferably administered orally. The composition is preferably comprised of at least vitamin B6, chamomile extract, passionflower extract, lemon balm extract, L-Theanine, GABA, 5-Hydroxytryptophan, and melatonin, in pre-determined amounts. The composition can further comprise a palliative agent, and can be provided in the form of a capsule, powder, liquid or tablet.

The invention discloses an acer truncatum bunge-containing traditional Chinese medicine composition with a sleep improving function and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 2.5-3.5 parts of acer truncatum bunge and 1.5-2.5 parts of spina date seeds. The traditional Chinese medicine composition is a traditional Chinese medicine orally-taken preparation with the sleep promoting effect, has the effects of quieting the heart, soothing the nerves, tonifying qi, replenishing the blood and can significantly prolong the sleep time, shorten the sleep latency time and improve the sleep quality; in addition, the medicinal raw materials are easy to obtain, the extraction technology of medicinal effective ingredients are easy and convenient, input mass production is promoted, and the product quality is easy to control.

The invention belongs to the field of tradition Chinese medicine, and relates to a traditional Chinese medicine composition containing folium artemisiae argyi and being capable of treating insomnia and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15 to 23 parts of folium artemisiae argyi, 16 to 21 parts of spina date seed, 12 to 19 parts of amber, 10 to 17 parts of poria with hostwood, 13 to 17 parts of stem and leaf of thinleaf milkwort, 13 to 20 parts of arillus longan, 8 to 15 parts of ophiopogon root, 6 to 10 parts of Rhizoma Coptidis, 9 to 17 parts of Radix Platycodonis, 8 to 17 parts of lophatherum herb, 7 to 15 parts of cape jasmine, 6 to 11 parts of semen coicis and 7 to 12 parts of liquorice root. The traditional Chinese medicine composition provided by the invention has the efficacy of clearing liver to stop wind, tonifying Qi and relieving convulsion, nourishing the blood and tranquilization, soothing liver to smooth Qi and the like, has the effect of treating both manifestation and root cause of the disease on insomnia treatment, and is free of toxic and side effects.

A combination of (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide with a medicine capable of prolonging a slow-wave sleep time provides a preventive or therapeutic agent for sleep disorder that induces natural sleep, shortens sleep latency, increases deep sleep, excels in sleep maintenance and ensures an appropriate sleep time.

The invention discloses a traditional Chinese medicine composition for treating insomnia, which is mainly prepared from the following raw material drugs in portion by weight: 5 to 15 portions of dactylicapnos root, 3 to 10 portions of grassleaf sweelflag rhizome, and 1 to 5 portions of Szechuan lovage rhizome. The invention also discloses a method for preparing crude drug powder, active component liquid medicine and dry extract powder of the traditional Chinese medicine composition. The traditional Chinese medicine composition has a simple formulation, and has the efficacies of tranquilizing and allaying excitement, activating blood and promoting Qi. Pharmacodynamics research results show that the traditional Chinese medicine composition applied by lavage can remarkably shorten the sleep latency of mice induced by sodium pentobarbital of threshold dosage, prolong sleep time, strengthen the hypnotic effects of the sodium pentobarbital of the threshold dosage, induce the mice given with the sodium pentobarbital of the sub-threshold dosage, and strengthen the hypnotic effects of the sodium pentobarbital of the sub-threshold dosage.

The invention discloses a traditional Chinese medicine composition for treating insomnia, amnesia and low spirit and a method for preparing the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises, by weight, 500-800 parts of radix polygonum multiflorum preparata, 400-600 parts of herba epimedii, 200-500 parts of lucid ganoderma, 200-500 parts of semen ziziphi spinosae, 100-500 parts of lilium brownii, 100-400 parts of (prepared) rhizoma polygonati, 100-400 parts of fructus lycii, 100-400 parts of astragalus, 100-400 parts of salvia miltiorrhiza and 100-400 parts of radix glycyrrhizae. The method includes extracting medicinal plants or medicinal slices to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition and the method have the advantages that effects of replenishing qi, enriching blood and nourishing liver and kidneys can be realized by the traditional Chinese medicine composition; obvious curative effects can be realized for patients who suffer from low spirit, insomnia, amnesia, deafness, dim eyesight, hair loss or premature graying of hair due to deficiency of qi and blood and deficiency of livers and kidneys.

The invention discloses a melatonin preparation for improving sleeping and a preparation method thereof. The melatonin preparation is prepared from the following raw materials in parts by weight: 1 to 3 parts of melatonin, 130 to 170 parts of starch, 100 to 156 parts of white granulated sugar, 70 to 144 parts of dextrin, 2 to 6 parts of talcum powder, 2 to 6 parts of magnesium stearate and 0.2 to 2 parts of sodium carboxymethylcellulose. The melatonin preparation for improving sleeping has the characteristics of safety, no toxicity, good taste, less dose and no dependence. Tests show that the melatonin preparation has the advantages that the sleeping time of nembutal can be obviously extended, the hypnotic effect of subthreshold dose of the nembutal is cooperated, the sleep latency of the nembutal is shortened, and a function of obviously improving sleeping is realized.

The invention relates to a traditional Chinese medicinal composition for treating headache, a preparation method thereof and a detection method thereof. The traditional Chinese medicinal composition consists of uncaria, ligusticum wallichii, scorpion, angelica, bidentate achyranthes, white paeony root and liquoric root. The formulation may be pills, granules, hard capsules, soft capsules, tablets, drop pills or oral liquid and the like. The preparation has the characteristics of exact curing effect, desirable clinical symptom relieving effect, fewer side effects and low price. The detection method of the granules comprises lamina identification of uncaria, ligusticum wallichii, scorpion, angelica root and bidentate achyranthes and the content assay of the white paeony root.

Compositions are described comprising at least partially defatted meal from a plant source containing protein-bound tryptophan, preferably squash seeds, and, optionally, a carbohydrate source provided in an amount capable of facilitating transport of in vivo generated tryptophan across the blood brain barrier. Also described are dietary supplements, foods and beverages comprising the composition of the invention to reduce anxiety.

The invention discloses a tortoise small peptide. The tortoise small peptide has any one of the following amino acid sequences: W-W-Y-W-R-Hex; W-G-P-G-B; W-R-W-X-H-T-H-N-W. The invention further discloses a preparation method and application of the tortoise small peptide. The tortoise small peptide can significantly shorten the sleep latency period of mice and prolong the sleep time, has a good sleep promoting effect, is clear in structural composition, stable in physical and chemical properties, more controllable in quality and easier to guarantee in efficacy compared with existing polypeptides, can be prepared by a synthesis method, and is beneficial to reducing resource waste and lowering the production cost.

An intervention for sleep disorders comprises: collagen, a gelatin peptide, or the amino acid glycine; L-theanine; lactucopicrin, deoxylactucopicrin, or another lactucopicrin derivative; hyaluronic acid; epigallocatechin gallate; and quinic acid. The intervention helps regulate pro-inflammatory biomarkers that are often associated with insomnia development and progression. These biomarkers include cytokines and enzymes associated with tryptophan degradation. Inhibition of these enzymes and cytokines improves tryptophan availability and sleep quality, and allows individuals to sleep better with fewer side effects. The composition promotes high-quality, deep sleep.

The oral medicine for treating insomnia is prepared with the Chinese medicinal materials, including wild jujube seed 20-50 weight portions, corydalis tuber 3-10 weight portions, and anemarrhena 3-10 weight portions. Experiment shows that the oral medicine has high effects of tranquilizing and mesmerizing.

This invention provides a Chinese traditional medicinal composition belonging to the field of the Chinese traditional medicine. The composition is prepared by using the medical ingredients of American ginseng, infusing crease of manyprickle acanthopanax root, vinegar infused tortoise shell, lucid ganoderma, tatarinowii sweet flag rhizome, thin leaf milk word root, fleece flower root, Chinese magnolia vine fruit and zinc gluconate according to a given ratio. The composition has an excellent curative effect for child mental retardation. This invention also reveals preparing method.

Belonging to the field of compound drugs, the invention relates to pharmaceutical new use of loganin, especially the use of loganin in preparation of drugs or health care products for improving sleep. The loganin provided by the invention is one of the main chemical components of Cornaceae plant cornus officinalis, the chemical formula is C17H26O10, and the molecular weight is 390.38. Animal experiments confirm that loganin can significantly prolong the total sleep time of mice, and has the characteristic of dose dependent increase of sleep amount. Preliminary action mechanism study shows that loganin possibly induces sleep by increasing the level of 5-HT in mouse brain. To sum up, loganin can be prepared into drugs and health care products with sedative and hypnotic effects, the made dosage forms include granules, tablets, capsules, granules, electuaries, oral liquid, dripping pills, pellets or injections.

The invention discloses an application of acer truncatum to making healthcare food or medicine with a sleep improving function. Acer truncatum is a traditional Chinese medicine oral preparation with a sleep promoting effect and has an effect of quieting health and soothing nerves, it is proved through tests that sleeping time can be remarkably prolonged and sleep latency time can be shortened to a certain extent, it is shown that acer truncatum has a good sleep promoting effect, raw materials are easy to obtain, the effective component extraction process is simple, mass production is easy, and product quality is easy to control.