Composition with sedative effect and atomization preparation thereof

A composition and efficacy technology, applied in the field of medicine, can solve the problems of insignificant curative effect of neurasthenia, high volatility of volatile oil, poor stability and human body absorption, etc., and achieve the effects of shortening sleep latency, easy absorption, and prolonging sleep time.

Active Publication Date: 2014-09-24
湖州鼎翔科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, natural plant volatile oils are highly volatile, poor in stability and human absorption, even if they are made into capsules, they are still difficult to be absorbed by the human body
Currently used as medicine, its curative effect on the treatment of neurasthenia is not significant

Method used

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  • Composition with sedative effect and atomization preparation thereof
  • Composition with sedative effect and atomization preparation thereof
  • Composition with sedative effect and atomization preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Preparation of tea polyphenols:

[0055] Get 5kg of commercially available Longjing green tea leaves and coarsely pulverize them with a pulverizer. Reflux and extract twice with an aqueous solution containing 70vol% ethanol. For the first time, add an ethanol-water solution equivalent to 8 times the volume of green tea leaves, and reflux for 2 hours. For the second time, use 7 times the volume of ethanol-water solution, reflux for 1 hour, and combine the above The extract obtained by adding ethanol-water solution twice and refluxing. After filtering the extract, distill the filtrate under reduced pressure, reclaim ethanol, and collect the extract;

[0056] After the above extract is filtered to remove insoluble matter, the extract is concentrated to remove part of the water and used in the next process. Afterwards, mix the chloroform and the extract according to the volume ratio of 3:2, after fully stirring and standing for stratification, take the upper aqueous solut...

Embodiment 2

[0063] Preparation of lavender essential oil:

[0064] Weigh 5kg of dried lavender flowers (produced in Yili, Xinjiang. Air-dried for 1 week at room temperature of about 25°C), pulverize with a pulverizer, pass through a 40-mesh sieve, add 80L of water and soak for 3 hours. Distilled with water steam for 3.5 hours, collected the distillate, after static layering, collected the upper oil layer.

[0065] Add anhydrous sodium sulfate to the oil layer and dry to obtain 45 g of dried lavender volatile oil.

[0066] Mix 0.5 parts by weight of lavender volatile oil prepared above, 0.5 parts by weight of tea polyphenols prepared in Example 1, 1.0 parts by weight of vitamin E and 98 parts by weight of propylene glycol to prepare atomizer 2 (formula 2) .

Embodiment 3

[0068] Preparation of lavender essential oil:

[0069] Weigh 5kg of dried lavender flowers (produced in Yili, Xinjiang. Air-dried for 1 week at room temperature of about 25°C), pulverize with a pulverizer, pass through a 40-mesh sieve, add 100L of water and soak for 3 hours. Distilled with water steam for 3 hours, collected the distillate, after standing for stratification, collected the upper oil layer;

[0070] Add anhydrous sodium sulfate to the oil layer and dry to obtain 41 g of dried lavender volatile oil.

[0071] 1.0 parts by weight of lavender volatile oil obtained above, 10 parts by weight of tea polyphenols obtained in Example 1, 1.0 parts by weight of vitamin E and 88 parts by weight of propylene glycol were mixed to prepare atomizer 3.

[0072] Carry out pharmacological experiment with the nebulizer obtained in embodiment 1 and embodiment 2.

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Abstract

The invention provides a composition with a sedative effect and an atomization preparation thereof. The composition comprises chamomile volatile oil or lavender volatile oil, tea polyphenol and vitamin E, has sedative and tranquillizing effects, no toxic and side effects and good stability, is easy to absorb by a human body and can effectively inhibit symptoms like neurasthenia.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a composition with sedative effect and an atomized preparation using the composition. Background technique [0002] With the rapid development of modern society and economy, the pace of urbanization and industrialization is accelerating, people's life rhythm is also accelerating and the pressure is increasing. More and more people are experiencing anxiety, worry, entanglement, insomnia, mental stress, depression, and mania. and other symptoms of neurasthenia. According to incomplete statistics, the incidence of neurasthenia accounts for more than 10% of the normal population in developing countries, and as high as 20% in developed countries. Neurasthenia has seriously affected people's quality of life. [0003] Neurasthenia can directly lead to the damage of multiple systems of the human body, and cause diseases such as hypertension, arrhythmia, cerebrovascular disease, diabetes and kidn...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K36/53A61K36/82A61K9/12A61P25/20A61K31/353A61K31/355
Inventor 冯小平赵家振陈钰
Owner 湖州鼎翔科技有限公司
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