5 results about "Sedative effect" patented technology

To provide an adjustment device capable of adjusting a biological rhythm and a life rhythm of an object person.SOLUTION: An adjustment device (40) includes a spray device (41) that supplies a substance having an awakening effect or a sedative effect to an object space (S) in which an object (T) is present, and a control device (100). The control device (100) controls the spray operation of the spray device (41) based on a biological rhythm of an object (T) and reference data serving as a reference of the biological rhythm, or based on a life rhythm of the object (T) and reference data serving as a reference of the life rhythm.SELECTED DRAWING: Figure 3

This invention relates to a levotetrahydropalmatine citrate, its preparation method, and its applications, belonging to the field of pharmaceutical technology. This invention provides a levotetrahydropalmatine citrate. Studies have shown that compared to other salt forms, the citrate form of levotetrahydropalmatine significantly improves its solubility. Furthermore, research has confirmed that levotetrahydropalmatine citrate can significantly reduce drug relapse preferences, with efficacy comparable to or even better than the injectable form, without causing significant adverse reactions and exhibiting good safety. Simultaneously, the sedative effect of levotetrahydropalmatine citrate is far superior to other salt forms. In addition, levotetrahydropalmatine citrate has therapeutic effects on sleep disorders, effectively shortening sleep onset time, increasing sleep duration, and improving sleep quality. Therefore, the levotetrahydropalmatine citrate provided by this invention has broad application prospects in the preparation of drugs for sedation, analgesia, treatment of sleep disorders, and treatment of drug addiction.

The application belongs to the technical field of biological medicine, and specifically discloses application of benserazide hydrochloride in preparation of anxiolytic drugs. The application first finds that benserazide hydrochloride plays an anxiolytic role by regulating the kynurenine metabolic pathway. Animal experiments prove that benserazide hydrochloride can promote the generation of kynurenine and its downstream metabolite 3-hydroxyanthranilic acid, and maintain the stable level of 3-hydroxykynurenine, thereby improving the function of the metabolic pathway and restoring the nervous system homeostasis. Behavioral experiments show that benserazide hydrochloride can increase the exploration behavior of zebrafish and reduce the avoidance behavior, and meanwhile, does not cause inhibition of motor function or sedative effect, and shows good safety and selectivity. The application provides a theoretical basis and a new drug source for the prevention and / or treatment of anxiety.

The application provides a new compound with local anesthesia and general deep sedation function and medical use. The new compound has the structure shown in the following formula: The compound has local anesthesia and also exhibits a unique general sedative effect, suggesting that it has general anesthesia potential, and its rapid onset and recovery characteristics make it possible to be used for developing a new intravenous anesthetic.