63 results about "Sedative effect" patented technology

This invention relates to personalized pharmaceutical kits, packaging, compositions, and methods for treatment of a mammal, comprising at least one antihistamine for treating an allergic disease or condition in a mammal, in combination with at least one wakefulness promoting agent for preventing sedative effects during day time use, while promoting the antihistamine and sedating effect during evening use.

Compositions, systems, and methods that can be used with a pressurized metered dose inhaler are disclosed. A pharmaceutical composition for use in a pressurized metered dose inhaler can comprise a cannabinoid composition, a co-solvent, a terpene composition, and a propellant. A pharmaceutical composition may be soluble. A system can comprise a plurality of cannabinoid compositions and/or a plurality of terpene compositions available in various combinations. One of a plurality of cannabinoid compositions and terpene composition combinations may be user-selectable in response to various factors such as a desired therapeutic benefit, sedative effect, flavor profile, or a combination of the foregoing. A method of formulating a soluble pMDI pharmaceutical composition comprising a cannabinoid composition, a co-solvent, a terpene composition, and a propellant is disclosed.

It is intended to provide a sedative effect-imparting agent that provides excellent sedative effect with good fragrance-releasing property, and is possible to provide the excellent sedative effect immediately.

The sedative effect-imparting agent according to the present invention provides excellent sedative effect immediately, since it consists of dimethoxybenzene that provides excellent sedative effect with good fragrance-releasing property.

The invention provides a method for refining and purifying 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazole-2-yl]-1-piperidine]ethyl]-alpha, alpha-dimethyl phenylacetic acid (Bilastine). Bilastine is used for treating allergic rhinitis and chronic idiopathic urticaria, has good safety and does not have the sedative effect and cardiac toxicity of common antihistamine drugs. In most of Bilastine preparation processes, the impurity content is high, and stubborn impurities are difficult to remove. The method for refining and purifying Bilastine, provided by the invention, comprises the steps of dissolving a crude product of Bilastine into a hot mixed solvent, cooling, precipitating, filtering, washing and drying to obtain high-purity Bilastine, wherein the impurity content meets the requirements.

The invention belongs to the technical field of research and development of pharmaceutical products, and relates to preparation and a sedative effect of an acanthopanax fruit compound tablet. A method for preparing the acanthopanax fruit compound tablet comprises the following steps of: refluxing and extracting 150g of acanthopanax fruits by using 75% ethanol with an amount of 8 to 10 times that of the acanthopanax fruits, and merging filtrates; extracting 100g of radix polygalae and 100g of shizandra by water with an amount of 8 to 10 times that of the radix polygalae and the shizandra, and merging filtrates; mixing the filtrates of the radix polygalae, the shizandra and the acanthopanax fruits, and recovering a solvent as an extractum; taking 300g of oyster shells, cleaning and breaking by a hammer; putting oyster shell fragments in a Muffle furnace to be calcined at a constant temperature of 900 DEG C for 2h, grinding the calcined fragments into powder by a mortar after cooling, and screening the powder by a 100-mesh sieve; putting the oyster shell powder in an enamel tray, adding the hot extractum, stirring quickly and evenly, adding an appropriate amount of starch to form a soft material, making the soft material into granules through a 14-mesh sieve, and spreading the granules in the enamel tray, drying dried at 60 DEG C in an oven; adding 3% talcum powder according to the weight of the dried granules, mixing evenly, screening the granules through the 14-mesh sieve, and tabletting. The invention has the sedative effect, and is suitable for industrial production.

The invention discloses haw pulp and a preparation method for the same. The haw pulp consists of the following raw materials: haws, softening water, ethylene diamine tetraacetic acid, white granulated sugar, citric acid and tea polypehnol. The preparation method comprises the following steps of selection of the raw materials; sepal, stem and kernel removal; softening and pulping; color protection; sugaring and concentration; acidity regulation; bottling and sealing for inspection; and sterilization and cooling. The haw pulp and the preparation method have the characteristics that the product is red or red brown, uniform, consistent and free of foreign smell and impurities, smells aromatic, tastes sour-sweet and delicious, has unique flavor, the peculiar flavor of haws and the healthcare effects of preventing and treating cardiovascular diseases, reducing blood pressure and cholesterols, softening blood vessels, inducing diuresis, achieving a sedative effect and the like, is particularly suitable for Chinese consumers, can be independently eaten, and can also be used as an accessory for food such as breads, pastries and instant noodles; the addition of pigments is avoided, original color and nutritional ingredients of haws are perfectly maintained, and the haw pulp is suitable for the old and the young.

The invention discloses application of longitudinal stripe xylaria. The application is characterized in that sporocarp or alcohol extract of the longitudinal stripe xylaria can be applied to preparing a composition with a sedative effect, a composition with a hypnotic effect and a composition used for treating insomnia or anxiety; the compositions are medicine compositions or food compositions or health-care product compositions. The sporocarp of the longitudinal stripe xylaria is obtained through artificial culture, and the alcohol extract of the longitudinal stripe xylaria is obtained through extraction and concentration. The sporocarp or the alcohol extract of the longitudinal stripe xylaria has the remarkable sedative-hypnotic effect, is a natural active material for researching and developing novel health-care food and new medicine with the sedative-hypnotic effect, can be used for treating nervous system diseases such as insomnia or anxiety or convulsions, and is good in effect.

The invention relates to a composition for reducing fish catching and transportation stress and a preparation method and application thereof, and belongs to the technical field of fishery breeding. The composition is prepared from the following components in parts by weight: 10 to 40 parts of flos daturae, 10 to 40 parts of Atropa belladonna, 5 to 20 parts of rhizoma arisaematis, 5 to 25 parts of semen ziziphi spinosae, 5 to 25 parts of pepper, 5 to 25 parts of mint and 1 to 5 parts of multivitamins. The composition has a good sedative effect, proper anesthesia depth and small damage to the liver, and can improve the immunity of live fishes, reduce caught casualties of fishes cultured in a pond, reduce the death rate of caught fishes in the transportation process and improve the survival rate of the caught fishes in temporary culture or re-culture.

The invention relates to a 4-methoxy methyl-4-(N-propionyl) aniline piperidine compound and a preparation method and application thereof. The structure of the compound is shown in Formula (I), wherein n is 2 or 3 and R is optional. The compound has good water solubility and stability and can achieve analgesic and sedative effects simultaneously. Thus, the compound is applicable to analgesia and sedation of patients needing postoperative care, and is particularly conducive to operation of the automatic dosing system by patients, and the operations by anesthesia doctors can be reduced.

The invention provides a use of ferulic acid in preparation of a drug for resisting mammal anxiety and provides a novel antianxiety drug having good effects and small side effects. Ferulic acid is an effective component of the antianxiety drug. Results of mouse elevated plus-maze test, hole-board test and spontaneous activity test on ferulic acid shows that ferulic acid has substantial antianxiety effects and no calmness effect and thus adverse reactions such as fatigue and somnolence caused by calmness effects of the existing antianxiety drug are avoided.

Therapeutic compositions of doxepin and having a preponderance of the cis doxepin isomer over the trans doxepin isomer provide therapeutic effects for affective, painful, or allergic disorders without the sedative effects commonly experienced with compositions having a preponderance of the trans doxepin isomer.

The invention discloses a compound anesthetic for a rat and a preparation method thereof and belongs to the field of preparation and application of animal compound anesthetics. The invention discloses the compound anesthetic for the rat for the first time. The compound anesthetic comprises dexmedetomidine, midazolam, oxycodone, a buffer solution and water for injection. The invention further discloses the preparation method of the compound anesthetic for the rat. The preparation method comprises the following steps: dissolving the above components in the water for injection; diluting; filtering; pilling in an ampoule bottle; and sterilizing to obtain. The compound anesthetic for the rat disclosed by the invention is quick in anesthesia induction, long in anesthesia maintenance time, good in antalgic and sedative effects and stable in revival, and the main influence on physiological and biochemical indexes of the rat is within the physiological range tolerance. The compound anesthetic is simple to operate and can be used for complex or long-term operations of the rat.

The invention discloses a chamomile essential oil bath salt, comprising, by weight, 2 to 4 parts of chamomile essential oil, 1 to 3 parts of sodium cetostearyl sulfate, 1 to 3 parts of lauryl dimethyl sulfobetaine and 100 parts of sodium sesquicarbonate. The chamomile essential oil bath salt provided by the invention can remove dirt in pores of a body, has an excellent sedative effect and is capable of relieving the skin.

The invention discloses a sedative pressure reduction magnet pillow. The sedative pressure reduction magnet pillow comprises a pillow inner, a pillow case in which the pillow inner is wrapped, and magnets fixed on the pillow case. The sedative pressure reduction magnet pillow is characterized in that the magnets are natural magnets adapting to human bodies, the magnets are uniformly distributed on the outer surface of the pillow case in a small nipple-like bump mode, multiple honeycomb air vents are arranged between the pillow case and the pillow inner, and the pillow inner is filled with wild chrysanthemum flowers, mint, Ligusticum wallichii, silktree flowers, tuber fleeceflower stems, bamboo leaves and gardenias. The sedative pressure reduction magnet pillow is advantaged in that, the sedative effect is not only realized, but also pressure reduction is realized, and massage health care efficacy is obvious.

The invention discloses a joint pain relieving plaster for osteoarthritis pains. The joint pain relieving plaster comprises Chinese medicinal raw materials of achyranthes bidentata, radix clematidis, rhizoma drynariae, cortex acanthopanacis, cassia twigs, mulberry twigs, frankincense, myrrh, caulis spatholobi, ground beetles, gentiana macrophylla, angelica, aconite, Szechuan lovage rhizome, ephedra, sodium sulfate, kansui roots, phryma, asarum, borneol, safflower, lycopodii herb, radix aconite and obscured homalomenarhizome. The invention discloses the joint pain relieving plaster for the osteoarthritis pains, which is prepared by adopting a plurality of Chinese herbal medicines soaked in a secret-made medicinal liquid added in the preparation process, and the joint pain relieving plaster is obtained by further fumigation of secret-made fumigation materials. Through many years of clinical experience of the inventor, the joint pain relieving plaster can effectively relive and treat the osteoarthritis pains, and further can eradicate the osteoarthritis pains after long-term use; the sticking plaster uses cotton cloth, does not contain any irritating smell of the traditional sticking plaster while being used, and further does not stimulate or damage skin; furthermore, the joint pain relieving plaster has light rosin fragrance, thereby not only treating a disease, but also having a very good sedative effect.

The invention relates to the technical field of compound essential oil, and discloses compound essential oil which takes grapefruit flowers as a main component and has a sedative effect, and the compound essential oil is prepared from the following raw materials in parts by weight: grapefruit flower essential oil, left hand essential oil, wild chrysanthemum flower essential oil, pelargonium graveolens essential oil, rosemary essential oil and golden wormwood. According to the compound essential oil with the grapefruit flowers as the main component and the sedative effect, the grapefruit flower essential oil has a good sedative effect and is matched with the left hand essential oil, the wild chrysanthemum flower essential oil, the pelargonium graveolens essential oil, the rosemary essential oil and the golden wormwood, so that the anorexia mood caused by single use of the grapefruit flower essential oil can be effectively avoided; the left hand essential oil, the wild chrysanthemum flower essential oil, the pelargonium graveolens essential oil, the rosemary essential oil and the golden wormwood also have a sedative effect, and cooperate with the pomelo flower essential oil to improve the sleep effect, meanwhile, a pure natural extraction mode is adopted, no pollution is caused, and the sedative effect of the compound essential oil is effectively improved through efficacy verification and formula screening.

The invention discloses an antibacterial and anti-allergic body wash, which comprises the following raw materials in parts by weight: 15-25 parts of fatty alcohol polyoxyethylene ether sodium sulfate, 6-12 parts of coconut oleic acid, 5-10 parts of rice bran oil, and snake gallbladder extract 3 to 5 parts of musk, 2 to 5 parts of musk, 1 to 3 parts of glycerin, 0.1 to 1 part of thickener, 0.5 to 1 part of preservative, and the balance is water. The sum of the parts by weight of the above-mentioned components is 100 parts. share. Snake gallbladder extract and musk are added to the body wash of the present invention, wherein the snake gallbladder extract has the functions of clearing away heat and detoxification, reducing inflammation and inhibiting bacteria, regulating sebum secretion and tightening skin, etc., and musk has the effects of analgesic and tranquilizing, dredging channels and collaterals, promoting blood circulation Blood stasis, anti-inflammatory pain relief and anti-inflammatory detoxification and other functions, through the addition of these two components, the body wash has the effect of anti-inflammatory and anti-bacterial while having the basic decontamination ability, and can form a protective film on the skin to effectively prevent Bacteria infestation; at the same time, musk has a natural fragrance, which has the effect of soothing the mind, enlightening the mind and calming the nerves.

The invention discloses a device for sleep rehabilitation treatment by using hydrogen. The device comprises a machine body, wherein an air outlet hole is formed in one side of a surface of the machine body, a main power source and an auxiliary power source are installed in the machine body, a water tank is installed in the machine body, an electrolyzer is installed in the water tank, a current output end of the main power supply is electrically connected with a current input end of the electrolyzer, the electrolyzer electrolyzes a water body to generate hydrogen and oxygen, and an effect of inducing the sleep incidence rate by the hydrogen is similar to that of diazepam, so that the sucked hydrogen has a certain effect of improving sleep quality, and the hydrogen does not have dependence and addiction compared with the diazepam, a pulse wave generator generates pulse waves after being powered on, brain nerves are adjusted, a sedation effect is facilitated, internal hydrogen is inhaled to adjust an internal circulation system of a body, external pulse waves adjust the brain nerve environment, internal and external cooperation is more effective for the insomnia, and insomnia treatment efficiency and quality are improved.

The present invention relates to a nutritional product, especially a soothing health food, which is composed of the following components in parts by weight: 20-23 parts of Mimosa, 25-30 parts of Sedum Sanqi, 23-27 parts of Jujube, longan 30-33 servings of meat, 21-24 servings of jujube seed, 5-25 servings of spirulina, 5-25 servings of mountain ballast, 1-5 servings of pollen, 1-5 servings of inulin. The nerve-soothing health food of the invention has the functions of nourishing blood, calming the nerves and calming down, has simple process, is convenient to drink, has good effect, and has good health-care effect on human body after long-term consumption.