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Compound salvia miltiorrhiza concentrated preparation and preparation and detection method thereof

A technology of compound salvia miltiorrhiza and concentrate, which is applied in the field of compound salvia miltiorrhiza concentrate tablet and its preparation, and can solve the problems of medicinal crop withering and the like

Active Publication Date: 2014-01-01
SINOPHARM GUANGDONG GLOBAL PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

What's more serious is that due to the massive die-off of medicinal crops, the shortage will become more and more serious in the future

Method used

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  • Compound salvia miltiorrhiza concentrated preparation and preparation and detection method thereof
  • Compound salvia miltiorrhiza concentrated preparation and preparation and detection method thereof
  • Compound salvia miltiorrhiza concentrated preparation and preparation and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The extraction of embodiment 1 salvia miltiorrhiza

[0070] The research on the extraction process of Salvia miltiorrhiza is as follows:

[0071] Influencing factors include: the amount of 95% ethanol, 50% ethanol, and water (both expressed in multiples of the amount of medicinal materials). Orthogonal test is used to optimize the process of extracting the amount of each solvent, select L 9 (3 4 ) orthogonal table, focusing on the above three factors, taking tanshinone II A The content of danshensu and the content of danshensu are the investigation indexes, and the factor level table is shown in table 1 below.

[0072] Table 1. Level list of salvia miltiorrhiza extraction process factors

[0073]

[0074] Test method: Weigh 50g of Salvia miltiorrhiza, numbered 1-9, press L 9 (3 4 ) orthogonal table arrangement test, the test results are shown in Table 2 below:

[0075] Table 2, L 9 (3 4 ) Orthogonal test list

[0076]

[0077] Table 3. Tan...

Embodiment 2

[0082] The alcohol precipitation of embodiment 2 salvia miltiorrhiza extract

[0083] 1. Research data on alcohol precipitation process of Danshen:

[0084] The influencing factors of the investigation are: the relative density of the extract, the alcohol precipitation concentration, and the alcohol precipitation time. The orthogonal test is used to optimize the alcohol precipitation process, and the L 9 (3 4 ) orthogonal table, focusing on the above three factors, taking tanshinone II A The content of danshensu and the content of danshensu are the investigation indexes, and the factor level table is shown in table 5 below.

[0085] Table 5, list of process factor levels for Alcohol Extraction of Salvia Miltiorrhiza

[0086]

[0087] Test method: Weigh 50g of Salvia miltiorrhiza, numbered 1-9, press L 9 (3 4 ) Orthogonal table arrangement test, the test results are shown in Table 6 below:

[0088] Table 6, L 9 (3 4 ) Orthogonal test list

[0089]

...

Embodiment 3 10

[0096] The alcohol extraction of embodiment 3 Panax notoginseng

[0097] The influencing factors are: crushing degree of medicinal materials, ethanol concentration, ethanol dosage, extraction frequency and extraction time. Orthogonal test is used to optimize the alcohol extraction process, select L 18 (3 7 ) orthogonal table, focusing on the above-mentioned five factors, taking the content of ginsenoside as the investigation index, and the factor level table is shown in Table 9.

[0098] Table 9, list of process factor levels for alcohol extraction of notoginseng

[0099]

[0100] Test method: Weigh 100g of Panax notoginseng, numbered 1-18, press L 18 (3 7 ) Orthogonal table arrangement test, the test results are shown in Table 10:

[0101] Table 10. Contents of ginsenosides in extracts extracted under different conditions (L 18 (3 7 ) Orthogonal Experiment List)

[0102]

[0103]

[0104] Table 11. Ginsenoside content variance analysis table ...

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Abstract

The invention provides a preparation method of compound salvia miltiorrhiza concentrated tablets and a product prepared by the same. By the preparation method, traditional equipment is not required to be replaced and only a part of parameters is required to be changed, so the cost for a changing process is greatly reduced and the method is easy to accept by manufacturers. The effective component extraction efficiency in a Chinese herbal medicine is improved by the preparation method; the prepared product has a very good effect; and very considerable economical and social benefits can be brought.

Description

technical field [0001] The invention relates to a compound salvia miltiorrhiza concentrated tablet for promoting blood circulation and removing stasis and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Traditional Chinese medicine is an important means of preventing and treating coronary heart disease. According to the dialectical theory of motherland medicine, two methods of treating the symptoms and treating the root cause are adopted. For palliative treatment, it is mainly used in the pain stage, mainly "tong", there are treatment methods such as promoting blood circulation, removing stasis, regulating qi, etc.; Conditioning the lungs and other methods. Among them, "promoting blood circulation and removing stasis" (commonly used medicinal materials such as salvia miltiorrhiza, safflower, Chuanxiong, turmeric) and "aromatic warming method" (commonly used Suhexiang pills, Baoxin pills, etc.) are the mos...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537G01N30/36A61P9/10A61K31/045
Inventor 向飞军朱颖虹黄掌欣
Owner SINOPHARM GUANGDONG GLOBAL PHARMA CO LTD
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