Preparation method of medicine for blood stasis of woman

A technology for diseases and medicines, applied in the field of medicine preparation, can solve the problems of low content of active ingredients and large dosage, and achieve the effects of high content of active ingredients and improved therapeutic effect

Active Publication Date: 2008-04-30
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its defect is: and the active ingredient content of the medicine prepared by this method is relatively low, and dosage is larger

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Example 1. A preparation method of a medicine for treating gynecological blood stasis disease, respectively weighing 720 grams of Guizhi, Poria, Moutan Bark, White Peony and Peach kernel, and the preparation steps are as follows: (1) Take Guizhi and pulverize into the coarsest powder, Use CO 2 The volatile oil was extracted by supercritical fluid to obtain cinnamon for use; the medicine residue and the peach kernel were extracted twice with 12 times the amount of water, and the peach kernels were boiled for 2 hours each time. The specific gravity measured at 45°C is 1.06). After cooling to room temperature, 95% ethanol is added to make the ethanol concentration 70%, the alcohol is precipitated for 24 hours, filtered, the supernatant is taken to recover the ethanol, concentrated, and vacuum dried at 80°C to obtain Extract I;

[0046] (2) Take Poria cocos by adding 8 times and 6 times the amount of 80% ethanol for reflux extraction twice for 1.5 hours each time, combine the e...

Embodiment 2

[0051] Example 2. A method for preparing a medicine for treating gynecological blood stasis disease, weighing 750 grams each of Chinese herbal medicines Guizhi, Poria, Moutan Bark, White Peony and Peach Kernel, and the preparation steps are as follows:

[0052] (1) Take cassia twig and crush it into the coarsest powder, use CO 2 The volatile oil is extracted by supercritical fluid to obtain cinnamon oil for use; the medicinal residue and peach kernels are extracted twice with 11 times the amount of water. The peach kernels are boiled for 1.5 hours each time. The extracts are combined and concentrated under reduced pressure to 1.5g medicinal materials per ml of medicinal liquid (The specific gravity is 1.04 measured at 45°C). After cooling to room temperature, 95% ethanol is added to make the ethanol concentration 70%, the alcohol is precipitated for 12 hours, filtered, the supernatant is taken to recover the ethanol, concentrated, and vacuum dried at 70°C. Get extract I;

[0053] ...

Embodiment 3

[0058] Example 3. A preparation method of a medicine for treating gynecological blood stasis disease, weighing 700 grams of Chinese herbal medicine Guizhi, Poria cocos, Moutan cortex, white peony root and peach kernel, and the preparation steps are as follows:

[0059] (1) Take cassia twig and crush it into the coarsest powder, use CO 2 The volatile oil is extracted by supercritical fluid to obtain cinnamon oil for later use; the medicinal residue and peach kernels are extracted twice with 10 times the amount of water. The peach kernels are boiled for 2 hours each time. The extracts are combined and concentrated under reduced pressure to 1.8g of medicinal liquid per ml. (The specific gravity is 1.08 measured at 50°C). After cooling to room temperature, 95% ethanol is added to make the ethanol concentration 75%, the alcohol is precipitated for 48 hours, filtered, the supernatant is taken to recover the ethanol, concentrated, and dried under vacuum at 65°C. Get extract I;

[0060] (...

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PUM

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Abstract

A Chinese medicine for treating the gynecologic blood stasis is prepared from cinammon twigs, tuckahoe, tree peony bark, white peony root and peach kernel through respectively extracting their active components, and adding medicinal auxiliary.

Description

Technical field [0001] The invention relates to a preparation method of a medicine using Chinese herbal medicine as a raw material, in particular to a preparation method of a medicine for treating gynecological blood stasis disease. Background technique [0002] In the prior art, the application number applied by the applicant is 01815449.2, and the patent entitled "A Chinese herbal medicine composition and its preparation method" discloses a pharmaceutical composition for the treatment of gynecological blood stasis disease, which is Capsules are made from cassia twig, white peony root, tuckahoe, peach kernel and tree peony bark according to the required weight ratio through the steps of steam distillation, ethanol extraction, concentration, granulation, and drying. The pharmaceutical composition has the characteristics of definite curative effect, no toxic and side effects, controllable quality standard, and easy absorption. The disadvantage is that the effective ingredient cont...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61K36/71A61K36/54A61K36/076A61K9/16A61K9/20A61K9/48A61P15/00
Inventor 肖伟戴翔翎廖正根邹红仲艳柳于介张孝法
Owner JIANGSU KANION PHARMA CO LTD
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