Pharmaceutical composition and application thereof to preparation of medicament for treating cerebrovascular disease
A technology for cerebrovascular disease and a composition, which is applied in the application field of preparing medicines for treating cerebrovascular disease, can solve the problems of unknown degree, low purity, abnormal liver function, etc., so as to reduce the effective dose, increase the therapeutic effect and toxicity. small effect
A technology for cerebrovascular disease and a composition, which is applied in the application field of preparing medicines for treating cerebrovascular disease, can solve the problems of unknown degree, low purity, abnormal liver function, etc., so as to reduce the effective dose, increase the therapeutic effect and toxicity. small effect
CN102485223AInactive Publication Date: 2012-06-06JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD
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Experimental program
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Embodiment 1
[0018] Get Edaravone 2g (gram), add in the propylene glycol solution of 200g, stir and make it dissolve completely, slowly add water for injection and make it dissolve and reach 1000ml (milliliter), to obtain final product.
Embodiment 2
[0020] Take 2 g of (+)-2-camphor, add it to 200 g of propylene glycol solution, stir to dissolve completely, slowly add water for injection to dissolve to 1000 ml, and obtain.
Embodiment 3
[0022] Take 1 g of (+)-2-camphor, add it to 200 g of propylene glycol solution, stir to dissolve it completely, slowly add water for injection to dissolve it to 1000 ml, and obtain.
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Abstract
A pharmaceutical composition comprises 3-methyl-1-phenyl-2-pyrazoline-5-ketone and (+)-2-borneol. The pharmaceutical composition can be used in treating cerebrovascular disease and has lower toxic and side effects.
Description
technical field [0001] The invention relates to a pharmaceutical composition and its application in the preparation of medicines for treating cerebrovascular diseases. Background technique [0002] Cerebrovascular disease is a group of diseases that seriously endanger human health, and has become one of the important causes of human disability and death. [0003] Cerebrovascular disease (CVD for short) refers to brain lesions caused by abnormalities in cerebrovascular vessels. Stroke generally refers to acute cerebrovascular disease. [0004] Cerebrovascular diseases can be simply divided into two categories, one is ischemic cerebrovascular disease caused by the reduction or interruption of blood flow, and the other is hemorrhagic cerebrovascular disease caused by rupture of blood vessels. Ischemic cerebrovascular disease is mainly cerebral infarction (including cerebral thrombosis and cerebral embolism). In addition to cerebral infarction, there is another type of ischemi...
Claims
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Patent Timeline
06 Jun 2012
Publication
CN102485223A
- IPC
- A61K31/4152; A61K31/045; A61P9/10
- Inventors
- 杨士豹; 华垚