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Traditional Chinese medicine compound preparation for treating gastric cancer and preparation method thereof

A technology of compound preparations and traditional Chinese medicines, which is applied in the direction of medical formulas, medical preparations containing active ingredients, antineoplastic drugs, etc., and can solve problems such as toxic side effects, poor selectivity, and low survival rate

Inactive Publication Date: 2012-07-25
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to its poor selectivity, radiotherapy and chemotherapy often produce relatively large toxic and side effects on normal tissue cells and organs, reduce the patient's immunity, reduce the patient's quality of life, and even shorten the patient's survival time. The 5-year survival rate is very low.

Method used

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  • Traditional Chinese medicine compound preparation for treating gastric cancer and preparation method thereof
  • Traditional Chinese medicine compound preparation for treating gastric cancer and preparation method thereof
  • Traditional Chinese medicine compound preparation for treating gastric cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The weight proportion of used Chinese medicinal material raw material is:

[0018]

[0019] Preparation:

[0020] (1) Get mixture I after getting Atractylodes Rhizoma Atractylodes Rhizome and Zedoary Rhizoma of various weights, add water equivalent to 10 times the weight of the mixture in Mixture I, soak for 1 hour, extract volatile oil by distillation for 3 hours, and extract the remaining medicinal liquid after volatile oil A for later use, add β-cyclodextrin equivalent to 6 times the weight of the obtained volatile oil to the extracted volatile oil, and clathrate at 50°C for 2 hours, and clathrate for later use;

[0021] (2) Collect the above medicinal liquid A, filter to obtain medicinal residue A, add water equivalent to 10 times the weight of medicinal residue to medicinal residue A, decoct for 1 hour, filter to obtain medicinal liquid B and medicinal residue B, discard medicinal residue B, combine medicinal liquid A and medicinal liquid B, heat and concentrat...

Embodiment 2

[0026] The weight proportion of used Chinese medicinal material raw material is:

[0027]

[0028]

[0029] Preparation method: with embodiment one.

Embodiment 3

[0031] The weight proportion of used Chinese medicinal material raw material is:

[0032]

[0033] Preparation method: with embodiment one.

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Abstract

The invention provides a traditional Chinese medicine compound preparation for treating gastric cancer and a preparation method thereof. The compound preparation is characterized by comprising the following raw materials in parts by weight: 50-300 parts of largehead atractylodes rhizome, 30-220 parts of immature bitter orange, 20-350 parts of pseudostellaria heterophylla, 20-370 parts of curcuma zedoary, 10-200 parts of lotus leaf, 200-1800 parts of Chinese date, 50-300 parts of bittersweet herb, 50-200 parts of medicinal citron, 80-350 parts of coix seed, 60-280 parts of vinegar rhizoma corydalis and 30-200 parts of pseudobulb of appendiculate cremastra. The traditional Chinese medicine materials are used as the raw materials to be prepared into the preparation. The compound preparation has the advantages of scientific prescription, obvious effects and little side effects, is easy to produce and take, and can be used for effectively treating the gastric cancer at progressive stage (moderate and advanced stage). After surgery and radiotherapy and chemotherapy, patients can take the compound preparation for treatment, thereby effectively preventing the spreading, relapse and metastasis of cancer cells.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular is a compound Chinese medicine preparation for treating gastric cancer, which takes Chinese herbal medicines as raw materials. Background technique: [0002] The annual incidence rate of gastric cancer in the world is 17.6% / 100,000 people, and its mortality rate accounts for 23.03% of malignant tumors in my country, ranking first. However, the onset of gastric cancer is insidious, there are often no specific clinical symptoms in the early stage, and the lesion develops rapidly. Most gastric cancer patients have already reached the middle and late stage when the diagnosis is confirmed, so advanced gastric cancer is more common clinically. At present, the first choice for the treatment of gastric cancer is radical surgery, combined with postoperative radiotherapy and chemotherapy. However, gastric cancer is prone to relapse and metastasis. For patients with...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/00A61P35/00
Inventor 孙蓉曹志群吕莉莉韩涛孙建光黄伟赵红龚彦胜
Owner SHANDONG ACAD OF CHINESE MEDICINE
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