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Veterinary medicine composition for preventing and treating mycotoxin pathopoiesia

A technology for mycotoxins and compositions, applied in the field of veterinary drug compositions, can solve the problems of decreased lean meat rate, decreased vaccine protection, decreased immunity of pigs, etc., and achieves the effects of eliminating damage and improving detoxification ability.

Inactive Publication Date: 2013-11-27
河南中亚神鹏医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] ①The incidence of various diseases increases: PRRS, circovirus, pseudorabies, swine fever, chlamydial disease, toxoplasmosis, etc. are often troubled; ②Production performance decreases: Feed intake decreases or food refusal leads to growth of pig herds Slow, the feed remuneration decreases, and the lean meat rate is also greatly reduced; ③The body’s tissue and organ damage: intestinal damage, increased diarrhea; kidney disease, bloody urine and watery stools; liver damage, decreased function; lung damage, increased acute pulmonary edema, etc.; ④ Decreased immunity of pigs: The protection of vaccines is greatly reduced, the pigs are seriously contaminated, the effect of drug treatment is poor, and the mortality rate is greatly increased
In fact, the mold remover can only remove part of the mold, and has no effect on the removal and removal of mycotoxins and most of the mold

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: The veterinary drug used to prevent sows from taking mildewed feed to cause disease is made of the following raw materials in parts by weight:

[0029] Antifungal agent (sodium diacetate) 15 parts, sodium humate 15 parts, montmorillonite 15 parts, rhubarb 15 parts, scutellaria baicalensis 15 parts, berberine 15 parts, licorice 10 parts, Radix Radix 15 parts, dry and pulverize the above net materials After passing through an 80-mesh sieve, weigh the ingredients according to the above ratio, mix, check the uniformity, and pack.

[0030] Method of use: For mildly moldy feed, the present invention mixes 1000kg according to 1000g; for moderate moldy feed, the present invention mixes 500kg according to 1000g; it is not recommended for severely moldy feed.

[0031] The above-mentioned veterinary drugs have been clinically applied in large-scale pig farms:

[0032] Experimental materials: There are about 600 sows in a large-scale pig farm in Puyang. 50 healthy s...

Embodiment 2

[0039] Embodiment 2: The veterinary drug for treating piglets caused by taking mildewed feed is made from the following raw materials in parts by weight:

[0040] 10 parts of antifungal agent, 20 parts of sodium humate, 5 parts of montmorillonite, 10 parts of rhubarb, 20 parts of skullcap, 5 parts of berberine, 15 parts of licorice, and 20 parts of isatidis. The preparation method and usage method are the same as in Example 1.

[0041] In a pig farm in Henan Province, 90 piglets were raised. Since the beginning of June 2011, the piglets have successively experienced the same symptoms: split limbs, vomiting, diarrhea, paralysis, etc., and the symptoms of death have gradually appeared, and multiple treatments have not improved. Later, the applicant went to see a doctor and found that the feed had produced moderate mildew. Afterwards, 500 kilograms of mixing materials per 1000 g of this embodiment were used to add 500 kilograms of feed to the feed, and at the same time cooperate ...

Embodiment 3

[0042] Embodiment 3: the veterinary medicine that is used to treat fattening pig and cause disease due to taking moldy feed, this medicine mainly comprises the raw material of following parts by weight: antifungal agent 20 parts, sodium humate 25 parts, montmorillonite 15 parts, rhubarb 25 parts, 5 parts of Scutellaria baicalensis, 25 parts of Coptis chinensis, 15 parts of licorice, and 25 parts of Radix Radix. The preparation method and usage method are the same as in Example 1.

[0043] The above-mentioned veterinary drugs have been tested for clinical application in large-scale pig farms, and the results of the specific implementation plan of the test are shown in the following test report.

[0044] Selection of test pigs: There are about 450 fattening pigs in a large-scale pig farm in Shandong, of which 89 fattening pigs have asthma and enteritis, which are found to be caused by mycotoxins in the feed. They are randomly divided into two groups , 50 pigs in random test gro...

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Abstract

The invention relates to a veterinary medicine composition for preventing and treating mycotoxin pathopoiesia. The veterinary medicine composition is prepared from the follow ingredients in parts by weight: 5 to 25 parts of mildew preventive, 5 to 25 parts of sodium humate, 5 to 25 parts of montmorillonite, 5 to 25 parts of rheum officinale, 5 to 25 parts of scutellaria baicalensis, 5 to 25 parts of coptis chinensis, 5 to 15 parts of liquorice and 5 to 25 parts of radix isatidis. The veterinary medicine composition has the advantages that the specific adsorption capacity is realized, various mycotoxins can be directionally and effectively eliminated, the veterinary medicine composition effectively aims at zearalenone, vomitoxin, aflatoxin, ochratoxin, fumitremorgin, T-2 toxin and the like, the detoxification capability of the liver per se on the toxin can be improved, and the toxin injury to animal bodies is eliminated.

Description

technical field [0001] The invention relates to a veterinary drug composition, in particular to a veterinary drug composition for preventing and treating diseases caused by mycotoxins. Background technique [0002] Mycotoxins are secondary metabolites produced by molds during their growth that are highly toxic to animals, humans and crops. There are currently more than 300 types of mycotoxins known. The toxins produced by various molds are different, and the degree of harm caused is also different. Among them, the most toxic ones are: aflatoxin, ochratoxin, snake toxin, fumatoxin, zearalenone, deoxynivalenol, T2 toxin, etc. These toxins have caused immeasurable harm to the development of the entire animal husbandry industry and even human health. The main hazards caused by mycotoxins to pigs are: [0003] ①The incidence of various diseases increases: PRRS, circovirus, pseudorabies, swine fever, chlamydial disease, toxoplasmosis, etc. are often troubled; ②Production perfo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/718A61P31/10A61K35/02A61K33/06
Inventor 杨党伟陈娟
Owner 河南中亚神鹏医药科技有限公司
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