Non-linear high-efficiency model construction method and application for prediction and evaluation of phenol toxicity to photobacteria

A toxicity prediction, non-linear technique, applied in the field of chemistry
CN103077313BInactive Publication Date: 2016-12-28HUNAN AGRICULTURAL UNIV
4 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUNAN AGRICULTURAL UNIV
Publication Date
2016-12-28
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a novel nonlinear high-efficient model building method and application of phenols for toxicity prediction and evaluation of photogenic bacteria. A non-linear SVR (Sustained Virological Response) technology is utilized to carry out QSAR (Quantitative Structure Activity Relationship) research on the toxicity of the photogenic bacteria represented as logEC50 through eighteen phenol compounds in the prior art. The work aims to look for a more reliable QSAR model with more reasonable characteristics through a nonlinear chemometric tool based on low-dimension characteristic data and high-dimension characteristic data, and analyze in detail the most valuable model relative to the toxicity and the most important molecular characteristic thereof. The novel nonlinear high-efficient model building method and the application of the phenols for the toxicity prediction and evaluation of the photogenic bacteria provide effective theoretical references for the design of phenol analogues for strengthening or weakening the toxicity of the photogenic bacteria.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of chemistry, and relates to a construction method and application of a non-linear high-efficiency model for predicting and evaluating the toxicity of phenol to photobacteria. Background technique

[0002] With the rapid development of the economy, the environmental problems related to chemicals have become increasingly prominent. Therefore, the toxicity risk assessment of organic pollutants is very important. Phenol is one of the most common environmental pollutants, especially in wastewater. Phenol is considered an environmental pollutant of priority concern due to its toxicity and persistence in the environment. Bright luminescent bacteria (Photobacterium phosphoreum) is a kind of luminescent bacteria in seawater, and its light intensity changes with the inhibition of bacterial growth (ie, cell density) by toxic substances, making it an important indicator for chemical toxicity measurement and water qual...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More