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Traditional Chinese medicine composition and preparation for treating mammary gland hyperplasia and preparation method thereof

A technology of mammary gland hyperplasia and composition, which is applied in the direction of drug combination, disease, medical formula, etc., can solve the problems of unsatisfactory curative effect, worrying side effects of western medicine, and few varieties of Chinese patent medicines, and achieve good anti-mammary gland hyperplasia, stable process, The effect of a large safety factor

Active Publication Date: 2014-10-15
重庆航月数云科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, among the medicines for the treatment of this disease, the side effects of western medicine are worrying, and traditional Chinese medicine is more commonly used, but there are very few Chinese patent medicines that can effectively relieve pain, and the curative effect is not satisfactory

Method used

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  • Traditional Chinese medicine composition and preparation for treating mammary gland hyperplasia and preparation method thereof
  • Traditional Chinese medicine composition and preparation for treating mammary gland hyperplasia and preparation method thereof
  • Traditional Chinese medicine composition and preparation for treating mammary gland hyperplasia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 Traditional Chinese medicine composition for treating mammary gland hyperplasia disease

[0036] It is composed of the following raw materials by weight:

[0037] Angelica 10, Pueraria 11, Dodder 18, Wang Bu Liuxing 22.5, Malt 15, Kunbu 18, Yanhu 16, Tongcao 10;

[0038] Or: Angelica 15, Pueraria 15, Cuscuta 22.5, Wang Bu Liuxing 7.5, Malt 18, Kunbu 14, Yanhu 22.5, Tongcao 8;

[0039] Or: Angelica 24, Pueraria 27, Dodder 10, Wang Bu Liuxing 12, Malt 6, Kunbu 9, Yanhu 14, Tongcao 15;

[0040] Or: Angelica 30, Pueraria 9, Dodder 7.5, Wang Bu Liuxing 18, Malt 9, Kunbu 6, Yanhu 7.5, Tongcao 5;

[0041] Or: Angelica 20, Pueraria 18, Dodder 15, Wang Bu Liuxing 15, Malt 12, Kunbu 12, Yanhu 15, Tongcao 10.

Embodiment 2

[0042] Example 2 Preparation of extracts of traditional Chinese medicine compositions for treating mammary gland hyperplasia

[0043] (1) pulverize the crude drug of each weight portion ratio described in Example 1 into coarse powder respectively, for subsequent use;

[0044] (2) Take Angelica sinensis coarse powder, add water to soak, extract and collect volatile oil, collect filter residue I and aqueous solution and keep in another device;

[0045] (3) Under the condition of 40~42℃, the above-mentioned volatile oil is clathrated with β-cyclodextrin, and stirred for 1~1.5 hours; then, under the condition of 2~4℃, refrigerate for 8~12 hours, and after suction filtration, the obtained After the inclusion compound is washed with a small amount of water and petroleum ether, it is dried for 8 to 10 hours under the condition of lower than 40°C, ground finely, and passed through a 60-80 mesh sieve, for use;

[0046] (4) Add 6 to 10 times the amount of water to the filter residue I ...

Embodiment 3

[0050] Embodiment 3 Preparation of traditional Chinese medicine granules containing the extract of the traditional Chinese medicine composition for the treatment of mammary gland hyperplasia

[0051] Get the extract of the Chinese medicine composition for the treatment of mammary gland hyperplasia prepared in Example 2, add dextrin, starch and microcrystalline cellulose, wherein the mass ratio of dextrin, starch and microcrystalline cellulose to the extract of the Chinese medicine composition is 0.2-0.4: 0.4-0.5: 0.4-0.6: 1, mix well, granulate, dry, and pack to make traditional Chinese medicine granules.

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Abstract

The invention relates to a traditional Chinese medicine composition and preparation for treating proliferative diseases of mammary gland and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following bulk drugs in parts by weight: 10-30 parts of Chinese angelica, 9-27 parts of the root of kudzu vine, 7.5-22.5 parts of the seed of Chinese dodder, 7.5-22.5 parts of the seed of cowherb, 6-18 parts of malt, 6-18 parts of kelp, 7.5-22.5 parts of corydalis tuber and 5-15 parts of ricepaper pith. The invention also relates to an extractive of the traditional Chinese medicine composition treating proliferative diseases of mammary gland. The invention further relates to a traditional Chinese medicine preparation including the extractive of the traditional Chinese medicine composition for treating proliferative diseases of mammary gland and a preparation method of the traditional Chinese medicine preparation which is an oral preparation. The traditional Chinese medicine preparation consists of the extractive of the traditional Chinese medicine composition for treating proliferative diseases of mammary gland and common medicine auxiliary materials of the corresponding dosage form, has the pharmacological function of resisting hyperplasia of mammary gland, resisting inflammation, relieving pain, promoting blood circulation and removing blood stasis without bringing no side effects; and the traditional Chinese medicine preparation can be used for treating female hyperplasia of mammary gland, breast lump and breast distending pain and has low dosage of medication, thereby having good market prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating hyperplasia of mammary glands, and also to a traditional Chinese medicine preparation composed of an extract of the traditional Chinese medicine composition for treating hyperplasia of mammary glands and conventional pharmaceutical excipients and a preparation method thereof. Background technique [0002] Breast hyperplasia is a common breast disease in women. It can occur at any age after puberty. It is more common in women aged 25 to 45. The incidence rate is 70% to 80%, ranking first in various breast diseases. The disease is essentially a disorder of the normal structure of the mammary gland caused by physiological hyperplasia and involution insufficiency. It is clinically characterized by breast lumps and breast pain. The symptoms are generally aggravated in the premenstrual period and relieved afte...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61P15/14
Inventor 姚干何宗玉
Owner 重庆航月数云科技有限公司
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